The treatment of Cushing's disease

R Pivonello, M De Leo, A Cozzolino… - Endocrine …, 2015 - academic.oup.com
Abstract Cushing's disease (CD), or pituitary-dependent Cushing's syndrome, is a severe
endocrine disease caused by a corticotroph pituitary tumor and associated with increased …

Cushing's syndrome

A Lacroix, RA Feelders, CA Stratakis, LK Nieman - The lancet, 2015 - thelancet.com
Chronic exposure to excess glucorticoids results in diverse manifestations of Cushing's
syndrome, including debilitating morbidities and increased mortality. Genetic and molecular …

Treatment of Cushing's syndrome: an endocrine society clinical practice guideline

LK Nieman, BMK Biller, JW Findling… - The Journal of …, 2015 - academic.oup.com
Objective: The objective is to formulate clinical practice guidelines for treating Cushing's
syndrome. Participants: Participants include an Endocrine Society-appointed Task Force of …

Cushing's syndrome: epidemiology and developments in disease management

ST Sharma, LK Nieman, RA Feelders - Clinical epidemiology, 2015 - Taylor & Francis
Cushing's syndrome is a rare disorder resulting from prolonged exposure to excess
glucocorticoids. Early diagnosis and treatment of Cushing's syndrome is associated with a …

Cushing's syndrome

J Newell-Price, X Bertagna, AB Grossman, LK Nieman - The Lancet, 2006 - thelancet.com
Cushing's syndrome results from lengthy and inappropriate exposure to excessive
glucocorticoids. Untreated, it has significant morbidity and mortality. The syndrome remains …

Treatment of adrenocorticotropin-dependent Cushing's syndrome: a consensus statement

BMK Biller, AB Grossman, PM Stewart… - The Journal of …, 2008 - academic.oup.com
Objective: Our objective was to evaluate the published literature and reach a consensus on
the treatment of patients with ACTH-dependent Cushing's syndrome, because there is no …

Cushing's disease: pathobiology, diagnosis, and management

RR Lonser, L Nieman, EH Oldfield - Journal of neurosurgery, 2017 - thejns.org
Cushing's disease (CD) is the result of excess secretion of adrenocorticotropic hormone
(ACTH) by a benign monoclonal pituitary adenoma. The excessive secretion of ACTH …

Mortality in patients with pituitary disease

M Sherlock, J Ayuk, JW Tomlinson… - Endocrine …, 2010 - academic.oup.com
Pituitary disease is associated with increased mortality predominantly due to vascular
disease. Control of cortisol secretion and GH hypersecretion (and cardiovascular risk factor …

MANAGEMENT OF ENDOCRINE DISEASE: The burden of Cushing's disease: clinical and health-related quality of life aspects

RA Feelders, SJ Pulgar, A Kempel… - European journal of …, 2012 - academic.oup.com
Objective Cushing's disease (CD) is a rare endocrine disorder characterized by excess
secretion of ACTH due to a pituitary adenoma. Current treatment options are limited and …

Management of hormone-secreting pituitary adenomas

GU Mehta, RR Lonser - Neuro-oncology, 2017 - academic.oup.com
Pituitary adenomas are one of the most common primary central nervous system tumors and
have an estimated prevalence of 17%. Approximately half of pituitary adenomas secrete …