γδ T cells provide the early source of IFN-γ to aggravate lesions in spinal cord injury

G Sun, S Yang, G Cao, Q Wang, J Hao… - Journal of Experimental …, 2018 - rupress.org
Immune responses and neuroinflammation are critically involved in spinal cord injury (SCI).
γδ T cells, a small subset of T cells, regulate the inflammation process in many diseases, yet …

Synaptic rearrangement following axonal injury: Old and new players

AB Spejo, ALR Oliveira - Neuropharmacology, 2015 - Elsevier
Following axotomy, the contact between motoneurons and muscle fibers is disrupted,
triggering a retrograde reaction at the neuron cell body within the spinal cord. Together with …

Blood transcriptomic comparison of individuals with and without autism spectrum disorder: A combined‐samples mega‐analysis

DS Tylee, JL Hess, TP Quinn, R Barve… - American Journal of …, 2017 - Wiley Online Library
Blood‐based microarray studies comparing individuals affected with autism spectrum
disorder (ASD) and typically developing individuals help characterize differences in …

Mesenchymal stem cells engrafted in a fibrin scaffold stimulate Schwann cell reactivity and axonal regeneration following sciatic nerve tubulization

LP Cartarozzi, AB Spejo, RS Ferreira Jr… - Brain research …, 2015 - Elsevier
The present study investigated the effectiveness of mesenchymal stem cells (MSCs)
associated with a fibrin scaffold (FS) for the peripheral regenerative process after nerve …

The CatWalk XT® is a valid tool for objective assessment of motor function in the acute phase after controlled cortical impact in mice

J Walter, O Kovalenko, A Younsi, M Grutza… - Behavioural brain …, 2020 - Elsevier
Background Despite multiple experimental models of traumatic brain injury (TBI) being
available, objective assessment of gait and motor function in rodents remains difficult; …

MHC-I promotes apoptosis of GABAergic interneurons in the spinal dorsal horn and contributes to cancer induced bone pain

Q Fu, D Shi, Y Zhou, H Zheng, H Xiang, X Tian… - Experimental …, 2016 - Elsevier
Cancer induced bone pain (CIBP) remains one of the most intractable clinical problems due
to poor understanding of its underlying mechanisms. Recent studies demonstrate the …

Immunological responses to transgene-modified neural stem cells after transplantation

N Wei, Z Sun, J Yu, Y Jia, P Zheng, H Tang… - Frontiers in …, 2021 - frontiersin.org
Neural stem cell (NSC) therapy is a promising therapeutic strategy for stroke. Researchers
have frequently carried out genetic modification or gene editing of stem cells to improve …

Focal lesion size poorly correlates with motor function after experimental traumatic brain injury in mice

J Walter, J Mende, S Hutagalung, M Grutza, A Younsi… - Plos one, 2022 - journals.plos.org
Background It remains unclear whether neurobehavioral testing adds significant information
to histologic assessment of experimental traumatic brain injury (TBI) and if automated gait …

Synaptic plasticity and sensory-motor improvement following fibrin sealant dorsal root reimplantation and mononuclear cell therapy

SU Benitez, R Barbizan, AB Spejo… - Frontiers in …, 2014 - frontiersin.org
Root lesions may affect both dorsal and ventral roots. However, due to the possibility of
generating further inflammation and neuropathic pain, surgical procedures do not prioritize …

Developmental expression and localization of MHC class I molecules in the human central nervous system

A Zhang, H Yu, Y He, Y Shen, Y Zhang, J Liu… - Experimental brain …, 2015 - Springer
Recent animal studies have found neuronal expression of major histocompatibility complex
(MHC) class I in the central nervous system (CNS). However, the developmental expression …