γδ T cells provide the early source of IFN-γ to aggravate lesions in spinal cord injury
Immune responses and neuroinflammation are critically involved in spinal cord injury (SCI).
γδ T cells, a small subset of T cells, regulate the inflammation process in many diseases, yet …
γδ T cells, a small subset of T cells, regulate the inflammation process in many diseases, yet …
Synaptic rearrangement following axonal injury: Old and new players
AB Spejo, ALR Oliveira - Neuropharmacology, 2015 - Elsevier
Following axotomy, the contact between motoneurons and muscle fibers is disrupted,
triggering a retrograde reaction at the neuron cell body within the spinal cord. Together with …
triggering a retrograde reaction at the neuron cell body within the spinal cord. Together with …
Blood transcriptomic comparison of individuals with and without autism spectrum disorder: A combined‐samples mega‐analysis
Blood‐based microarray studies comparing individuals affected with autism spectrum
disorder (ASD) and typically developing individuals help characterize differences in …
disorder (ASD) and typically developing individuals help characterize differences in …
Mesenchymal stem cells engrafted in a fibrin scaffold stimulate Schwann cell reactivity and axonal regeneration following sciatic nerve tubulization
LP Cartarozzi, AB Spejo, RS Ferreira Jr… - Brain research …, 2015 - Elsevier
The present study investigated the effectiveness of mesenchymal stem cells (MSCs)
associated with a fibrin scaffold (FS) for the peripheral regenerative process after nerve …
associated with a fibrin scaffold (FS) for the peripheral regenerative process after nerve …
The CatWalk XT® is a valid tool for objective assessment of motor function in the acute phase after controlled cortical impact in mice
J Walter, O Kovalenko, A Younsi, M Grutza… - Behavioural brain …, 2020 - Elsevier
Background Despite multiple experimental models of traumatic brain injury (TBI) being
available, objective assessment of gait and motor function in rodents remains difficult; …
available, objective assessment of gait and motor function in rodents remains difficult; …
MHC-I promotes apoptosis of GABAergic interneurons in the spinal dorsal horn and contributes to cancer induced bone pain
Q Fu, D Shi, Y Zhou, H Zheng, H Xiang, X Tian… - Experimental …, 2016 - Elsevier
Cancer induced bone pain (CIBP) remains one of the most intractable clinical problems due
to poor understanding of its underlying mechanisms. Recent studies demonstrate the …
to poor understanding of its underlying mechanisms. Recent studies demonstrate the …
Immunological responses to transgene-modified neural stem cells after transplantation
N Wei, Z Sun, J Yu, Y Jia, P Zheng, H Tang… - Frontiers in …, 2021 - frontiersin.org
Neural stem cell (NSC) therapy is a promising therapeutic strategy for stroke. Researchers
have frequently carried out genetic modification or gene editing of stem cells to improve …
have frequently carried out genetic modification or gene editing of stem cells to improve …
Focal lesion size poorly correlates with motor function after experimental traumatic brain injury in mice
J Walter, J Mende, S Hutagalung, M Grutza, A Younsi… - Plos one, 2022 - journals.plos.org
Background It remains unclear whether neurobehavioral testing adds significant information
to histologic assessment of experimental traumatic brain injury (TBI) and if automated gait …
to histologic assessment of experimental traumatic brain injury (TBI) and if automated gait …
Synaptic plasticity and sensory-motor improvement following fibrin sealant dorsal root reimplantation and mononuclear cell therapy
SU Benitez, R Barbizan, AB Spejo… - Frontiers in …, 2014 - frontiersin.org
Root lesions may affect both dorsal and ventral roots. However, due to the possibility of
generating further inflammation and neuropathic pain, surgical procedures do not prioritize …
generating further inflammation and neuropathic pain, surgical procedures do not prioritize …
Developmental expression and localization of MHC class I molecules in the human central nervous system
A Zhang, H Yu, Y He, Y Shen, Y Zhang, J Liu… - Experimental brain …, 2015 - Springer
Recent animal studies have found neuronal expression of major histocompatibility complex
(MHC) class I in the central nervous system (CNS). However, the developmental expression …
(MHC) class I in the central nervous system (CNS). However, the developmental expression …