The coronavirus pandemic, COVID-19 has a global impact on the lives and livelihoods of
people. It is characterized by a widespread infection by the severe acute respiratory …

Only a mere fraction of the huge variety of human pathogenic viruses can be targeted by the
currently available spectrum of antiviral drugs. The severe acute respiratory syndrome …

Treating a viral disease is no simple feat. Drug resistance, latent reservoirs in the body,
emerging novel viruses, and a frequent lack of specific treatments all complicate antiviral …

Endo-M, an endo-β-N-acetylglucosaminidase from Mucor hiemalis, is a family 85 glycoside
hydrolase. This enzyme is unique in that it can transfer en bloc the oligosaccharide of …

Attachment of the Influenza A virus onto host cells involves multivalent interactions between
virus surface hemagglutinin (HA) and sialoside-containing glyco ligands. Despite the …

Glycopolymers having pendant triazole-linked sialyloligosaccharides were successfully
synthesized from free saccharides without any protection of the hydroxy and carboxy groups …

Since 1997, several epizootic avian influenza viruses (AIVs) have been transmitted to
humans, causing diseases and even deaths. The recent emergence of severe human …

The high transmissibility and genetic variability of the influenza virus have made the design
of effective approaches to control the infection particularly challenging. The virus surface …

There is a broad interest in the development of nanoparticles (NPs) carrying on their surface
carbohydrates such as sialic acids. It is known that these carbohydrates influence the …

The annual flu season causes thousands of deaths and millions of hospitalizations, which
pose a great burden to global health and economy. Moreover, a flu pandemic arising from …