Flaviviruses are enveloped arthropod-borne viruses with a single-stranded, positive-sense
RNA genome that can cause serious illness in humans and animals. The 11 kb 5′ capped …

Dengue virus (DENV) genome amplification is a process that involves the viral RNA, cellular
and viral proteins, and a complex architecture of cellular membranes. The viral RNA is not a …

The new SARS-CoV-2 poses a significant threat to human health but many aspects of its
basic biology remain unknown. Its genome encodes accessory genes that differ significantly …

Arboviruses are transmitted by distantly related arthropod vectors such as mosquitoes (class
Insecta) and ticks (class Arachnida). RNA interference (RNAi) is the major antiviral …

The RNA genomes of plus-strand RNA viruses have the ability to form secondary and higher-
order structures that contribute to their stability and to their participation in inter-and …

ABSTRACT The 5′ untranslated region (5′ UTR) of the dengue virus (DENV) genome
contains two defined elements essential for viral replication. At the 5′ end, a large stem …

The genome of a pathogenic organism possesses a specific order of nucleotides that
contains not only information about the synthesis and expression of proteomes, which are …

Dengue virus (DENV) is an emerging mosquito-borne human pathogen that affects millions
of individuals each year by causing severe and potentially fatal syndromes. Despite intense …

Usutu virus (USUV) and West Nile virus (WNV) are two closely related emerging mosquito-
borne flaviviruses. Their natural hosts are wild birds, but they can also cause severe …

The positive sense genomes of members of the genus Flavivirus in the family Flaviviridae
are∼ 11 kb in length and have a 5′ type I cap but no 3′ poly-A. The 3′ and 5′ terminal …