Tumour fatty acid metabolism in the context of therapy resistance and obesity
Fatty acid metabolism is known to support tumorigenesis and disease progression as well
as treatment resistance through enhanced lipid synthesis, storage and catabolism. More …
as treatment resistance through enhanced lipid synthesis, storage and catabolism. More …
Lipids as mediators of cancer progression and metastasis
Metastasis formation is a complex process, involving multiple crucial steps, which are
controlled by different regulatory mechanisms. In this context, the contribution of cancer …
controlled by different regulatory mechanisms. In this context, the contribution of cancer …
[HTML][HTML] Ferroptosis heterogeneity in triple-negative breast cancer reveals an innovative immunotherapy combination strategy
F Yang, Y Xiao, JH Ding, X Jin, D Ma, DQ Li, JX Shi… - Cell metabolism, 2023 - cell.com
Treatment of triple-negative breast cancer (TNBC) remains challenging. Deciphering the
orchestration of metabolic pathways in regulating ferroptosis will provide new insights into …
orchestration of metabolic pathways in regulating ferroptosis will provide new insights into …
Metabolic fitness and plasticity in cancer progression
S McGuirk, Y Audet-Delage, J St-Pierre - Trends in cancer, 2020 - cell.com
Cancer cells have enhanced metabolic needs due to their rapid proliferation. Moreover,
throughout their progression from tumor precursors to metastases, cancer cells face …
throughout their progression from tumor precursors to metastases, cancer cells face …
Lipid metabolism and endocrine resistance in prostate cancer, and new opportunities for therapy
GE Stoykova, IR Schlaepfer - International journal of molecular sciences, 2019 - mdpi.com
Prostate cancer (PCa) is the most common cancer in men, and more than 10% of men will
be diagnosed with PCa during their lifetime. Patients that are not cured with surgery or …
be diagnosed with PCa during their lifetime. Patients that are not cured with surgery or …
Therapy-induced lipid uptake and remodeling underpin ferroptosis hypersensitivity in prostate cancer
Background Metabolic reprograming, non-mutational epigenetic changes, increased cell
plasticity, and multidrug tolerance are early hallmarks of therapy resistance in cancer. In this …
plasticity, and multidrug tolerance are early hallmarks of therapy resistance in cancer. In this …
Androgen receptor signaling and metabolic and cellular plasticity during progression to castration resistant prostate cancer
T Uo, CC Sprenger, SR Plymate - Frontiers in oncology, 2020 - frontiersin.org
Metabolic reprogramming is associated with re/activation and antagonism of androgen
receptor (AR) signaling that drives prostate cancer (PCa) progression to castration …
receptor (AR) signaling that drives prostate cancer (PCa) progression to castration …
Label-free imaging of lipid droplets in prostate cells using stimulated Raman scattering microscopy and multivariate analysis
EW Hislop, WJ Tipping, K Faulds… - Analytical …, 2022 - ACS Publications
Hyperspectral stimulated Raman scattering (SRS) microscopy is a powerful imaging
modality for the analysis of biological systems. Here, we report the application of k-means …
modality for the analysis of biological systems. Here, we report the application of k-means …
Prostate cancer progression: as a matter of fats
N Scaglia, YR Frontini-López, G Zadra - Frontiers in Oncology, 2021 - frontiersin.org
Advanced prostate cancer (PCa) represents the fifth cause of cancer death worldwide.
Although survival has improved with second-generation androgen signaling and Parp …
Although survival has improved with second-generation androgen signaling and Parp …
Role of lipids and lipid metabolism in prostate cancer progression and the tumor's immune environment
Simple Summary Cholesterol, lipids, and lipid metabolism are important in prostate cancer.
Lipid metabolism interacts with androgens which are of clear importance in prostate cancer …
Lipid metabolism interacts with androgens which are of clear importance in prostate cancer …