APOE and Alzheimer's disease: Pathologic clues from transgenic Drosophila melanogaster

M Haddadi, M Haghi, N Rezaei, Z Kiani… - Archives of Gerontology …, 2024 - Elsevier
Alzheimer's disease (AD) is one of the most common forms of neurodegenerative diseases.
Apolipoprotein E4 (ApoE4) is the main genetic risk factor in the development of late-onset …

[HTML][HTML] Arsenic impairs Drosophila neural stem cell mitotic progression and sleep behavior in a tauopathy model

TH Adebambo, MFM Flores, SL Zhang, DA Lerit - bioRxiv, 2024 - pmc.ncbi.nlm.nih.gov
Despite established exposure limits, arsenic remains the most significant environmental risk
factor detrimental to human health and is associated with carcinogenesis and neurotoxicity …

Huntingtin Plays a Role in the Physiological Response to Ethanol in Drosophila

EBD Clabough, C Aspili, WS Fussy… - Journal of …, 2023 - content.iospress.com
Background: Huntingtin (htt) protein is an essential regulator of nervous system function
through its various neuroprotective and pro-survival functions, and loss of wild-type htt …

From Natural Behavior to Drug Screening: Invertebrates as Models to Study Mechanisms Associated with Alcohol Use Disorders

H Scholz - 2023 - Springer
Humans consume ethanol-containing beverages, which may cause an uncontrollable or
difficult-to-control intake of ethanol-containing liquids and may result in alcohol use …

Chronic Exercise and the Treatment of Progressive Disorders

K Richardson - 2023 - search.proquest.com
Exercise is a known, beneficial treatment for a variety of normal (aging) and abnormal
(disease) declines in health. These benefits can be observed in a range of tissues, including …