Modern drug discovery methods led to evolving new agents with significant therapeutic
potential. However, their properties, such as solubility and administration-related …

The treatment of skin wounds caused by trauma and pathophysiological disorders has been
a growing healthcare challenge, posing a great economic burden worldwide. The use of …

The healing of bone defects after a fracture remains a key issue to be addressed. Globally,
more than 20 million patients experience bone defects annually. Among all artificial bone …

Developing new effective treatment strategies to overcome the rise in multi-drug resistant
tuberculosis cases (MDR-TB) represents a global challenge. A host-directed therapy (HDT) …

Pseudomonas aeruginosa (P. aeruginosa) is a common nosocomial pathogen that can
cause severe infections in critically ill patients. Due to its resistance to multiple drugs, it is …

With the accelerated development of nanotechnology in recent years, nanomaterials have
become increasingly prevalent in the medical field. The poly (lactic acid–glycolic acid) …

Staphylococcus aureus is a unique challenge for the healthcare system because it can form
biofilms, is resistant to the host's immune system, and is resistant to numerous antimicrobial …

This study aimed to develop an efficient nano-delivery system to treat MRSA-infected
diabetic wounds by continuously providing Lomefloxacin (Lome) in a constant pattern with …

Periodontal diseases, chronic inflammatory conditions affecting oral health, are primarily
driven by microbial plaque biofilm and the body's inflammatory response, leading to tissue …

The rapid increase in multidrug resistant biofilm infections is a major concern for global
health. A highly effective therapy is required for the treatment of biofilm related infections. In …