Main drivers of (poly) phenol effects on human health: metabolite production and/or gut microbiota-associated metabotypes?

CE Iglesias-Aguirre, A Cortés-Martín… - Food & function, 2021 - pubs.rsc.org
Despite the high human interindividual variability in response to (poly) phenol consumption,
the cause-and-effect relationship between some dietary (poly) phenols (flavanols and olive …

Bioavailability and metabolism of chlorogenic acids (acyl‐quinic acids) in humans

MN Clifford, A Kerimi… - Comprehensive Reviews in …, 2020 - Wiley Online Library
Acyl‐quinic acids (chlorogenic acids) are produced by many plants, including fruits,
vegetables, and herbal remedies, with coffee and maté particularly rich dietary sources …

Effect of gut microbiota biotransformation on dietary tannins and human health implications

IE Sallam, A Abdelwareth, H Attia, RK Aziz, MN Homsi… - Microorganisms, 2021 - mdpi.com
Tannins represent a heterogeneous group of high-molecular-weight polyphenols that are
ubiquitous among plant families, especially in cereals, as well as in many fruits and …

[HTML][HTML] Revisiting the bioavailability of flavan-3-ols in humans: A systematic review and comprehensive data analysis

G Di Pede, P Mena, L Bresciani, M Achour… - Molecular Aspects of …, 2023 - Elsevier
This systematic review summarizes findings from human studies investigating the different
routes of absorption, metabolism, distribution and excretion (ADME) of dietary flavan-3-ols …

Characterization of the Interindividual Variability Associated with the Microbial Metabolism of (−)-Epicatechin

J Lessard-Lord, C Roussel, V Guay… - Journal of Agricultural …, 2023 - ACS Publications
Although the relationship between gut microbiota and flavan-3-ol metabolism differs greatly
between individuals, the specific metabolic profiles, known as metabotypes, have not yet …

Effect of food structure and processing on (Poly) phenol–gut microbiota interactions and the effects on human health

FA Tomás-Barberán, JC Espín - Annual Review of Food Science …, 2019 - annualreviews.org
The two-way interaction of food (poly) phenols with the human gut microbiota has been
studied throughout the past ten years. Research has shown that this interaction can be …

[HTML][HTML] Factors driving the inter-individual variability in the metabolism and bioavailability of (poly) phenolic metabolites: A systematic review of human studies

C Favari, JFR de Alvarenga, L Sánchez-Martínez… - Redox Biology, 2024 - Elsevier
This systematic review provides an overview of the available evidence on the inter-
individual variability (IIV) in the absorption, distribution, metabolism, and excretion (ADME) …

Interaction between diet and microbiota in the pathophysiology of Alzheimer's disease: Focus on polyphenols and dietary fibers

A Ticinesi, L Mancabelli, L Carnevali… - Journal of …, 2022 - content.iospress.com
Animal studies increasingly indicate that the gut microbiota composition and function can be
involved in the pathophysiology and progression of Alzheimer's disease (AD) at multiple …

Bioavailability and metabolism of selected cocoa bioactive compounds: A comprehensive review

J Oracz, E Nebesny, D Zyzelewicz… - Critical reviews in …, 2020 - Taylor & Francis
Cocoa beans and their co-products are a rich source of beneficial compounds for health
promotion, including polyphenols and methylxanthines. Knowledge of bioavailability and in …

Assessing the Gut Microbiota's Ability to Metabolize Oligomeric and Polymeric Flavan‐3‐ols from Aronia and Cranberry

J Lessard‐Lord, C Roussel, V Guay… - Molecular Nutrition & …, 2024 - Wiley Online Library
Clinical trials investigating the health effects of flavan‐3‐ols yield heterogeneous results due
to interindividual variability in the gut microbiota metabolism. In fact, different groups in the …