[HTML][HTML] Potential and therapeutic roles of diosmin in human diseases
E Huwait, M Mobashir - Biomedicines, 2022 - mdpi.com
Because of their medicinal characteristics, effectiveness, and importance, plant-derived
flavonoids have been a possible subject of research for many years, particularly in the last …
flavonoids have been a possible subject of research for many years, particularly in the last …
Metabolism and pharmacological activities of the natural health-benefiting compound diosmin
Y Zheng, R Zhang, W Shi, L Li, H Liu, Z Chen, L Wu - Food & function, 2020 - pubs.rsc.org
Diosmin is a famous natural flavonoid for treating chronic venous insufficiency and varicose
veins. Recently, extensive study has indicated that diosmin possesses diverse …
veins. Recently, extensive study has indicated that diosmin possesses diverse …
Antioxidant and anti-inflammatory properties of flavonoids from lotus plumule
The antioxidant and anti-inflammatory mechanisms of action of flavonoids in lotus plumule
were systematically analyzed using radical scavenging assays and ELISA kits. By this …
were systematically analyzed using radical scavenging assays and ELISA kits. By this …
Pharmacology of diosmin, a citrus flavone glycoside: an updated review
SH Gerges, SA Wahdan, DA Elsherbiny… - European journal of …, 2022 - Springer
Flavonoids are phytochemicals that are well known for their beneficial pharmacological
properties. Diosmin is a flavone glycoside derived from hesperidin, a flavanone abundantly …
properties. Diosmin is a flavone glycoside derived from hesperidin, a flavanone abundantly …
Diosmin attenuates methotrexate‐induced hepatic, renal, and cardiac injury: A biochemical and histopathological study in mice
MM Abdel-Daim, HA Khalifa… - Oxidative medicine …, 2017 - Wiley Online Library
The current study was designed to investigate the beneficial role of diosmin, a biologically
active flavonoid, against methotrexate‐(MTX‐) induced hepatic, renal, and cardiac injuries in …
active flavonoid, against methotrexate‐(MTX‐) induced hepatic, renal, and cardiac injuries in …
Ablation of endothelial Pfkfb3 protects mice from acute lung injury in LPS-induced endotoxemia
L Wang, Y Cao, B Gorshkov, Y Zhou, Q Yang… - Pharmacological …, 2019 - Elsevier
Acute lung injury (ALI) is one of the leading causes of death in sepsis. Endothelial
inflammation and dysfunction play a prominent role in development of ALI. Glycolysis is the …
inflammation and dysfunction play a prominent role in development of ALI. Glycolysis is the …
Flavonoids as potential phytotherapeutics to combat cytokine storm in SARS‐CoV‐2
Emergence of severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) infection,
COVID‐19, has become the global panic since December 2019, which urges the global …
COVID‐19, has become the global panic since December 2019, which urges the global …
[HTML][HTML] Resveratrol mitigates lipopolysaccharide-mediated acute inflammation in rats by inhibiting the TLR4/NF-κBp65/MAPKs signaling cascade
G Wang, Z Hu, Q Fu, X Song, Q Cui, R Jia, Y Zou… - Scientific reports, 2017 - nature.com
Resveratrol (RSV) is a natural compound exhibiting anti-inflammatory effect, but the anti-
inflammatory mechanism has not been fully understood. This study is aimed to evaluate the …
inflammatory mechanism has not been fully understood. This study is aimed to evaluate the …
Design, synthesis and evaluation of ursodeoxycholic acid-cinnamic acid hybrids as potential anti-inflammatory agents by inhibiting Akt/NF-κB and MAPK signaling …
X Li, Y Hu, B He, L Li, Y Tian, Y Xiao, H Shang… - European Journal of …, 2023 - Elsevier
A series of ursodeoxycholic acid (UDCA)-cinnamic acid hybrids were designed and
synthesized. The anti-inflammatory activity of these derivatives was screened through …
synthesized. The anti-inflammatory activity of these derivatives was screened through …
[HTML][HTML] Diosmin mitigates dexamethasone-induced osteoporosis in vivo: Role of Runx2, RANKL/OPG, and oxidative stress
ESA Arafa, NO Elgendy, MA Elhemely… - Biomedicine & …, 2023 - Elsevier
Secondary osteoporosis is commonly caused by long-term intake of glucocorticoids (GCs),
such as dexamethasone (DEX). Diosmin, a natural substance with potent antioxidant and …
such as dexamethasone (DEX). Diosmin, a natural substance with potent antioxidant and …