Restoring O-glycosylation and expression of MUC2 limits progression of colorectal cancer

Y Yang, Y Yin, W Xu, Y Kang, J Chen, Y Zou, Z Xiao… - bioRxiv, 2024 - biorxiv.org
This study investigated the molecular mechanisms underlying the regulation of MUC2 O-
glycosylation in colorectal cancer. In addition, the potential of rosiglitazone to inhibit …

Role of ST6GAL1 and ST6GAL2 in subversion of cellular signaling during enteroaggregative Escherichia coli infection of human intestinal epithelial cell lines

S Chandel, A Joon, S Kaur, S Ghosh - Applied Microbiology and …, 2023 - Springer
Emerging evidence have suggested that aberrant sialylation on cell-surface carbohydrate
architecture may influence host–pathogen interactions. The α2, 6-sialyltransferase (ST) …

Pathogen-Induced Glycosylation Alterations: Untangling the Host Cell's Sweet Response

P Martinez-Morales - Pathogens Associated with the Development of …, 2024 - Springer
This chapter explores the intricate relationship between pathogens and host cell
glycosylation alterations. Glycosylation, a crucial post-translational modification, plays a …