100 years of suramin
N Wiedemar, DA Hauser, P Mäser - Antimicrobial agents and …, 2020 - Am Soc Microbiol
Suramin is 100 years old and is still being used to treat the first stage of acute human
sleeping sickness, caused by Trypanosoma brucei rhodesiense. Suramin is a …
sleeping sickness, caused by Trypanosoma brucei rhodesiense. Suramin is a …
Peptide dendrimers: applications and synthesis
K Sadler, JP Tam - Reviews in Molecular biotechnology, 2002 - Elsevier
Peptide dendrimers are radial or wedge-like branched macromolecules consisting of a
peptidyl branching core and/or covalently attached surface functional units. The multimeric …
peptidyl branching core and/or covalently attached surface functional units. The multimeric …
Suramin inhibits SARS-CoV-2 infection in cell culture by interfering with early steps of the replication cycle
C Salgado-Benvindo, M Thaler, A Tas… - Antimicrobial Agents …, 2020 - Am Soc Microbiol
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic that
originated in Wuhan, China, in December 2019 has impacted public health, society, the …
originated in Wuhan, China, in December 2019 has impacted public health, society, the …
The history of antiretrovirals: key discoveries over the past 25 years
E De Clercq - Reviews in medical virology, 2009 - Wiley Online Library
Abstract Within 25 years after zidovudine (3′‐azido‐2′, 3′‐dideoxythymidine, AZT) was
first described as an inhibitor of HIV replication, 25 anti‐HIV drugs have been formally …
first described as an inhibitor of HIV replication, 25 anti‐HIV drugs have been formally …
Microbial recognition of target-cell glycoconjugates
KA Karlsson - Current opinion in structural biology, 1995 - Elsevier
Attachment of microbial protein to host cell-surface carbohydrate is considered essential for
successful infection. Information of conceptual interest, including crystal structures of protein …
successful infection. Information of conceptual interest, including crystal structures of protein …
[图书][B] Synthetic multivalent molecules: concepts and biomedical applications
S Choi - 2004 - books.google.com
This book provides basic principles of multivalent interactions found in biological systems as
well as an up-to-date and thorough coverage in design concepts, syntheses, and biological …
well as an up-to-date and thorough coverage in design concepts, syntheses, and biological …
Suramin inhibits chikungunya virus replication through multiple mechanisms
IC Albulescu, M Van Hoolwerff, LA Wolters, E Bottaro… - Antiviral research, 2015 - Elsevier
Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that causes severe and often
persistent arthritis. In recent years, millions of people have been infected with this virus for …
persistent arthritis. In recent years, millions of people have been infected with this virus for …
Recent advances in multiple antigen peptides
JP Tam - Journal of Immunological Methods, 1996 - Elsevier
The goals for the development of multiple antigen peptides (MAP) are to provide a rational
and unambiguous system to multimerize different types of synthetic peptide antigens and to …
and unambiguous system to multimerize different types of synthetic peptide antigens and to …
[HTML][HTML] A time-of–drug addition approach to target identification of antiviral compounds
D Daelemans, R Pauwels, E De Clercq… - Nature protocols, 2011 - nature.com
Insight into the mode of action of newly discovered antiviral agents is now almost a
prerequisite for clinical development. This protocol describes a method that provides …
prerequisite for clinical development. This protocol describes a method that provides …
[HTML][HTML] Electrostatic surface potential as a key parameter in virus transmission and evolution: how to manage future virus pandemics in the post-COVID-19 era
Virus-cell interactions involve fundamental parameters that need to be considered in
strategies implemented to control viral outbreaks. Among these, the surface electrostatic …
strategies implemented to control viral outbreaks. Among these, the surface electrostatic …