Macular edema consists of intra-or subretinal fluid accumulation in the macular region. It
occurs during the course of numerous retinal disorders and can cause severe impairment of …

Lacking conventional lymphatic system, the central nervous system requires alternative
clearance systems, such as the glymphatic system, which promotes clearance of interstitial …

The glymphatic system, a fluid-clearance pathway involved in brain waste clearance, is
known to be impaired in neurological disorders, including Alzheimer's disease (AD). For this …

The discovery of the water specific channel, aquaporin, and abundant expression of its
isoform, aquaporin-4 (AQP-4), on astrocyte endfeet brought about significant advancements …

The neurovascular unit (NVU) is a conceptual framework that has been proposed to better
explain the relationships between the neural cells and blood vessels in the human brain …

Neurovascular pathology concurs with protein accumulation, as the brain vasculature is
important for waste clearance. Interstitial solutes, such as amyloid-β, were previously …

The complexity of the blood–brain barrier (BBB) and neurovascular unit (NVU) was and still
is a challenge to bridge. A highly selective, restrictive and dynamic barrier, formed at the …

In the past, water homeostasis of the brain was understood as a certain quantitative
equilibrium of water content between intravascular, interstitial, and intracellular spaces …

Idiopathic normal pressure hydrocephalus (iNPH) is a rare neurological disorder with no
clear prevalence factors and is a significant danger to the elderly. The intracranial …

Background As an alternative to advection, solute transport by shear-augmented dispersion
within oscillatory cerebrospinal fluid flow was investigated in small channels representing …