Drug consumption is driven by a drug's pharmacological effects, which are experienced as
rewarding, and is influenced by genetic, developmental, and psychosocial factors that …

The habenula (Hb) is a phylogenetically old epithalamic structure differentiated into two
nuclear complexes, the medial (MHb) and lateral habenula (LHb). After decades of search …

Binge alcohol consumption induces discrete social and arousal disturbances in human
populations that promote increased drinking and accelerate the progression of Alcohol Use …

Alcohol consumption afflicts men and women differently. However, the underlying neuronal
mechanisms that contribute to the difference are mostly unexplored. Although more men …

Compulsion-like alcohol drinking (CLAD), where consumption continues despite negative
consequences, is a major obstacle to treating alcohol use disorder. The locus coeruleus …

The scaffolding A-kinase anchoring protein 150 (AKAP150) is critically involved in kinase
and phosphatase regulation of synaptic transmission/plasticity, and neuronal excitability …

Synthetic gabapentinoids, exemplified by gapapentin and pregabalin, are in extensive
clinical use for indications including epilepsy, neuropathic pain, anxiety, and alcohol …

Alcohol Withdrawal Syndrome (AWS) is characterized as the termination of chronic and
sustained alcohol use that leads to severe symptoms of distress or loss of daily functions …

Anxiety disorders often co-occur with alcohol use disorders, but the mechanisms underlying
this comorbidity remain elusive. Previously, we reported that rats withdrawn from chronic …

Alcoholism and psychiatric disorders like depression and anxiety are often comorbid.
Although the mechanisms underlying this comorbidity are unclear, emerging evidence …