Microorganisms, including bacteria, viruses, fungi, and other eukaryotes, play critical roles in
human health. An altered microbiome can be associated with complex diseases …

The chemokine receptor CXCR2 and its ligands are implicated in the progression of tumours
and various inflammatory diseases. Activation of the CXCLs/CXCR2 axis activates multiple …

Tumour-induced granulocytic hyperplasia is associated with tumour vasculogenesis and
escape from immunity via T cell suppression. Initially, these myeloid cells were identified as …

Background Drug-resistance and severe side effects of chemotherapeutic agents result in
unsatisfied survival of patients with lung cancer. CXCLs/CXCR2 axis plays an important role …

Myeloid-derived suppressor cells (MDSCs) are a major component of the immune-
suppressive network described in cancer and many other pathological conditions. We …

Reactive oxygen species (ROS) are derivatives of molecular oxygen (O 2) involved in
various physiological and pathological processes. In immune cells, ROS are mediators of …

The role of redox molecules, such as NO and ROS, as key mediators of immunity has
recently garnered renewed interest and appreciation. To regulate immune responses, these …

Myeloid-derived suppressor cells (MDSCs) are one of the main cell populations responsible
for regulating immune responses. MDSCs accumulate during tumor progression …

Myeloid-derived suppressor cells (MDSC) play a key immunosuppressive role in various
types of cancer, including head and neck squamous cell carcinoma (HNSCC). In this study …

Until recently, the intrinsically high level of cross-talk between immune cells, the complexity
of immune cell development, and the pleiotropic nature of cytokine signaling have …