Introduction: In recent years, new drug delivery systems have attempted to overcome the
undesirable pharmacokinetic problems of various drugs. Among them, cyclodextrin …

Background Bortezomib (BTZ) as an anticancer drug has been used through the injection
pathway. Research design and methods Two types of Cyclodextrin nanosponges (CDNSs) …

AIM: In the present investigation, vancomycin (VCM) biodegradable nanoparticles were
developed for oral administration, with the aim of improving its intestinal permeability …

Introduction: There are many factors that can affect the absorption process of orally
administered drugs. Intestinal transporters play an important role in drug absorption. These …

Purpose: Azithromycin (AZI) is a new macrolide antibiotic with a better activity against
intracellular gram negative bacteria in comparison with Erythromycin. The purpose of this …

Purpose: P-glycoprotein (P-gp; ABCB1), an integral membrane protein in the apical surface
of human intestinal epithelial cells, plays a crucial role in the intestinal transport and efflux …

Purpose: The purpose of this work was to preparation of vancomycin (VCM) biodegradable
nanoparticles to improve the intestinal permeability, using water-in-oil-in-water (W/O/W) …

The objective of this study was to create a new method for delivering oral borneol (BN) drug
that would improve stability. This was accomplished through microencapsulation using …

Intestinal permeability is a key biopharmaceutical variable in pharmaceutical research and
development, and regulatory assessment. In situ rat models are often used to predict the …

The main objective of the present study was to determine the permeability of clarithromycin
(CLA)-PLGA nanoparticles using single-pass intestinal perfusion technique in rats …