Long‐Term PM2.5 Exposure and Risks of Ischemic Heart Disease and Stroke Events: Review and Meta‐Analysis

SE Alexeeff, NS Liao, X Liu… - Journal of the …, 2021 - Am Heart Assoc
Background Fine particulate matter< 2.5 µm in diameter (PM2. 5) has known effects on
cardiovascular morbidity and mortality. However, no study has quantified and compared the …

Review of acellular assays of ambient particulate matter oxidative potential: methods and relationships with composition, sources, and health effects

JT Bates, T Fang, V Verma, L Zeng… - … science & technology, 2019 - ACS Publications
Oxidative stress is a potential mechanism of action for particulate matter (PM) toxicity and
can occur when the body's antioxidant capacity cannot counteract or detoxify harmful effects …

Meteorological conditions, climate change, new emerging factors, and asthma and related allergic disorders. A statement of the World Allergy Organization

G D'Amato, ST Holgate, R Pawankar… - World allergy …, 2015 - Springer
The prevalence of allergic airway diseases such as asthma and rhinitis has increased
dramatically to epidemic proportions worldwide. Besides air pollution from industry derived …

ROS signaling in the pathogenesis of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS)

M Kellner, S Noonepalle, Q Lu, A Srivastava… - … redox signaling in …, 2017 - Springer
The generation of reactive oxygen species (ROS) plays an important role for the
maintenance of cellular processes and functions in the body. However, the excessive …

The toxicological mechanisms of environmental soot (black carbon) and carbon black: focus on oxidative stress and inflammatory pathways

R Niranjan, AK Thakur - Frontiers in immunology, 2017 - frontiersin.org
The environmental soot and carbon blacks (CBs) cause many diseases in humans, but their
underlying mechanisms of toxicity are still poorly understood. Both are formed after the …

Epithelial barrier dysfunction in chronic respiratory diseases

FM Carlier, C de Fays, C Pilette - Frontiers in physiology, 2021 - frontiersin.org
Mucosal surfaces are lined by epithelial cells, which provide a complex and adaptive
module that ensures first-line defense against external toxics, irritants, antigens, and …

Particulate matter air pollution and cardiovascular disease: an update to the scientific statement from the American Heart Association

RD Brook, S Rajagopalan, CA Pope III, JR Brook… - Circulation, 2010 - Am Heart Assoc
In 2004, the first American Heart Association scientific statement on “Air Pollution and
Cardiovascular Disease” concluded that exposure to particulate matter (PM) air pollution …

Oxidative stress and air pollution exposure

M Lodovici, E Bigagli - Journal of toxicology, 2011 - Wiley Online Library
Air pollution is associated with increased cardiovascular and pulmonary morbidity and
mortality. The mechanisms of air pollution‐induced health effects involve oxidative stress …

Composition of air pollution particles and oxidative stress in cells, tissues, and living systems

AJ Ghio, MS Carraway, MC Madden - Journal of Toxicology and …, 2012 - Taylor & Francis
Epidemiological studies demonstrated an association between increased levels of ambient
air pollution particles and human morbidity and mortality. Production of oxidants, either …

[图书][B] Hayes' principles and methods of toxicology

AW Hayes, T Kobets - 2023 - taylorfrancis.com
Hayes' Principles and Methods of Toxicology has long been established as a reliable and
informative reference for the concepts, methodologies, and assessments integral to …