Radiotherapy is used in> 50% of patients with cancer, both for curative and palliative
purposes. Radiotherapy uses ionizing radiation to target and kill tumour tissue, but normal …

The management of patients with cancer and Li-Fraumeni or heritable TP53-related cancer
syndromes is complex because of their increased risk of developing second malignant …

Purpose The physical properties of protons lower doses to surrounding normal tissues
compared with photons, potentially reducing acute and long-term adverse effects, including …

Background In radiotherapy, especially when treating children, minimising exposure of
healthy tissue can prevent the development of adverse outcomes, including second cancers …

AcknowledgmentsdThis PENTEC initiative was made possible, in part, by logistic support
from the American Association of Physicists in Medicine. This special supplement to the …

Purpose To investigate the relationship between oesophagus dose-volume distribution and
long-term risk of oesophageal cancer after radiation therapy for breast cancer. Materials and …

Anticancer regimens for Hodgkin lymphoma (HL) patients include highly genotoxic drugs
that have been very successful in killing tumor cells and providing a 90% disease-free …

Purpose In this Pediatric Normal Tissue Effects in the Clinic (PENTEC) vision paper,
challenges and opportunities in the assessment of subsequent neoplasms (SNs) from …

Purpose Synchronous bilateral irradiation of both mammary glands and chest wall is a
challenging task due to technical difficulties and limited evidence supporting an optimal …

It is established that moderate-to-high doses of ionising radiation increase the risk of
subsequent cancer in the exposed individual, but the question arises as to the risk of cancer …