The conceptual evolution of nicotinamide adenine dinucleotide (NAD+) from being seen as
a simple metabolic cofactor to a pivotal cosubstrate for proteins regulating metabolism and …

Cisplatin is a clinically advanced and highly effective anticancer drug used in the treatment
of a wide variety of malignancies, such as head and neck, lung, testis, ovary, breast cancer …

Curcumin is a phytochemical isolated from Curcuma longa with potent tumor‐suppressor
activity, which has shown significant efficacy in pre‐clinical and clinical studies. Curcumin …

Nicotinamide adenine dinucleotide (NAD), the cell's hydrogen carrier for redox enzymes, is
well known for its role in redox reactions. More recently, it has emerged as a signaling …

Cancer is the second leading cause of death in the world. Chemotherapy and radiotherapy
are the common cancer treatments. However, the development of adverse effects resulting …

Significance: A common link between all forms of acute and chronic kidney injuries,
regardless of species, is enhanced generation of reactive oxygen species (ROS) and …

Ageing is a plastic process and can be successfully modulated by some biomedical
approaches or pharmaceutics. In this manner it is possible to delay or even prevent some …

Significance: Nicotinamide adenine dinucleotide (NAD+) is an essential pyridine nucleotide
that serves as an essential cofactor and substrate for a number of critical cellular processes …

The efficacy of chemotherapy in cancer therapy is limited due to resistance, treatment
selectivity, and severe adverse effects. Immunotherapy, chemotherapy, targeted therapy …

The coenzyme nicotinamide adenine dinucleotide (NAD+) has key roles in the regulation of
redox status and energy metabolism. NAD+ depletion is emerging as a major contributor to …