Vaping, environmental toxicants exposure, and lung cancer risk

SA Shehata, EA Toraih, EA Ismail, AM Hagras… - Cancers, 2023 - mdpi.com
Simple Summary Lung cancer (LC) is considered one of the most common cancers globally.
Numerous studies have determined the relations between E-cigarette, or vaping, products …

Non-smoking-associated lung cancer: a distinct entity in terms of tumor biology, patient characteristics and impact of hereditary cancer predisposition

E Smolle, M Pichler - Cancers, 2019 - mdpi.com
Non-small cell lung cancer (NSCLC) in non-, and especially in never-smoking patients is
considered a biologically unique type of lung cancer, since risk factors and tumorigenic …

MicroRNA‑126: A new and promising player in lung cancer

Q Chen, S Chen, J Zhao, Y Zhou… - Oncology …, 2021 - spandidos-publications.com
Lung cancer is one of the most common malignant tumors associated with cancer death;
however, the mechanisms involved in lung tumor development have not been completely …

Epigenetic regulation of miRNA expression in malignant mesothelioma: miRNAs as biomarkers of early diagnosis and therapy

M Tomasetti, S Gaetani, F Monaco, J Neuzil… - Frontiers in …, 2019 - frontiersin.org
Asbestos exposure leads to epigenetic and epigenomic modifications that, in association
with ROS-induced DNA damage, contribute to cancer onset. Few miRNAs epigenetically …

Molecular fingerprints of malignant pleural mesothelioma: not just a matter of genetic alterations

E Lorenzini, A Ciarrocchi, F Torricelli - Journal of Clinical Medicine, 2021 - mdpi.com
Malignant pleural mesothelioma (MPM) is a clinical emergency of our time. Being strongly
associated with asbestos exposure, incidence of this cancer is ramping up these days in …

Role of microRNAs in lung carcinogenesis induced by asbestos

R Bersimbaev, O Bulgakova, A Aripova… - Journal of personalized …, 2021 - mdpi.com
MicroRNAs are a class of small noncoding endogenous RNAs 19–25 nucleotides long,
which play an important role in the post-transcriptional regulation of gene expression by …

ATG5 as biomarker for early detection of malignant mesothelioma

M Tomasetti, F Monaco, O Strogovets, L Volpini… - BMC Research …, 2023 - Springer
Objectives Malignant pleural mesothelioma (MPM) is an aggressive disease with grim
prognosis due to lack of effective treatment options. Disease prediction in association with …

[HTML][HTML] ING5 overexpression upregulates miR-34c-5p/Snail1 to inhibit EMT and invasion of lung cancer cells: ING5 targets miR-34c-5p/Snail1 axis to inhibit lung …

J Yang, X Liu, Y Sun, X Zhang, Y Zhao… - Acta Biochimica et …, 2023 - ncbi.nlm.nih.gov
ING5 belongs to the inhibitor of growth (ING) candidate tumor suppressor family, which is
involved in multiple cellular functions, such as cell cycle regulation, apoptosis, and …

[HTML][HTML] The role of MicroRNAs as early biomarkers of asbestos-related lung cancer: A systematic review and meta-analysis

D Mukhopadhyay, P Cocco, S Orru, R Cherchi… - Pulmonology, 2024 - Elsevier
Background Asbestos is still the leading cause of occupational cancer mortality worldwide.
Asbestos-related lung cancer (LC) and malignant pleural mesothelioma (MPM) prognosis is …

[HTML][HTML] Identification of the miRNA signature associated with survival in patients with ovarian cancer

SY Sathipati, SY Ho - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Ovarian cancer is a major gynaecological malignant tumor associated with a high mortality
rate. Identifying survival-related variants may improve treatment and survival in patients with …