Multiple sclerosis is a chronic, demyelinating disease of the CNS. Cognitive impairment is a
sometimes neglected, yet common, sign and symptom with a profound effect on instrumental …

Multiple sclerosis (MS) is the commonest non‐traumatic disabling disease to affect young
adults. The incidence of MS is increasing worldwide, together with the socioeconomic …

We sought to define the pathological features of myelin oligodendrocyte glycoprotein (MOG)
antibody associated disorders (MOGAD) in an archival autopsy/biopsy cohort. We …

Background Treatment of patients younger than 18 years of age with multiple sclerosis has
not been adequately examined in randomized trials. We compared fingolimod with …

Neuropsychiatric abnormalities may be broadly divided in two categories: disorders of
mood, affect, and behavior and abnormalities affecting cognition. Among these conditions …

Importance Cognitive impairment in multiple sclerosis (MS) can lead to reduced quality of
life, social functioning, and employment. Few studies have investigated cognitive outcomes …

Objective To evaluate long-term disability progression in pediatric-onset multiple sclerosis
(POMS) and compare to adult-onset multiple sclerosis (AOMS). Methods This was a …

Multiple sclerosis (MS) is an immune-inflammatory disease that attacks and damages
myelinated axons in the central nervous system (CNS) and causes nontraumatic …

Objective To characterize the use and safety of newer disease-modifying therapies (DMTs)
in children with multiple sclerosis (MS) and clinically isolated syndrome (CIS) treated under …

Objective To explore whether age at onset increased over time despite a shortened interval
from the initial clinical demyelinating event to the diagnosis of multiple sclerosis (MS), as …