Challenges and Frontiers in Computational Metabolic Psychiatry

AG Chesebro, BB Antal, C Weistuch… - Biological Psychiatry …, 2024 - Elsevier
One of the primary challenges in metabolic psychiatry is that the disrupted brain functions
that underlie psychiatric conditions arise from a complex set of downstream and feedback …

D-ꞵ-hydroxybutyrate stabilizes hippocampal CA3-CA1 circuit during acute insulin resistance

B Kula, B Antal, C Weistuch, F Gackière, A Barre… - PNAS …, 2024 - academic.oup.com
The brain primarily relies on glycolysis for mitochondrial respiration but switches to
alternative fuels such as ketone bodies (KBs) when less glucose is available. Neuronal KB …

[PDF][PDF] The metabolic costs of cognition

S Jamadar, A Behler, H Deery, M Breakspear… - 2024 - osf.io
1 The metabolic costs of cognition Sharna D Jamadar1,2, Anna Behler3, Hamish Deery1,2,
Michael J Breakspear3,4 1. School of Psyc Page 1 1 The metabolic costs of cognition Sharna D …

Ketosis Elevates Antioxidants and Enhances Neural Function Through Improved Bioenergetics: A 1H MR Spectroscopy Study

H van Nieuwenhuizen, BB Antal, A Hone-Blanchet… - bioRxiv, 2024 - biorxiv.org
Ketosis is known to alter the balance of neuroactive amino acids and enhance neural
function when compared to a glycolytic condition. However, its influence on other …