Current evidence for the use of sugammadex in children

JD Tobias - Pediatric Anesthesia, 2017 - Wiley Online Library
Sugammadex is a novel pharmacologic agent, which reverses neuromuscular blockade with
a mechanism that differs from the commonly used, acetylcholinesterase inhibitors. Although …

Efficacy and safety of sugammadex for the reversal of rocuronium-induced neuromuscular blockade in patients with end-stage renal disease: a systematic review and …

YS Kim, BG Lim, YJ Won, SK Oh, JS Oh, SA Cho - Medicina, 2021 - mdpi.com
Background and Objectives: Sugammadex is widely used in anesthesia to reverse
rocuronium-induced neuromuscular blockade (NMB). In patients with compromised kidney …

[PDF][PDF] Reversal (antagonism) of neuromuscular blockade

GS Murphy, HD De Boer, LI Eriksson, RD Miller - Miller's anesthesia, 2015 - academia.edu
• Appropriate reversal of a nondepolarizing neuromuscular blockade is essential to avoid
adverse patient outcomes. Complete recovery of muscle strength should be present, and the …

[HTML][HTML] Safety and efficacy of 4 mg· kg− 1 sugammadex for simultaneous pancreas-kidney transplantation recipients: a prospective randomized trial

J Tang, R He, L Zhang, S Xu - Annals of Transplantation, 2023 - ncbi.nlm.nih.gov
Background Simultaneous pancreas-kidney transplantation (SPK) is a time-consuming and
important surgical procedure, which can provide a physiological mean of achieving …

Perioperative anesthesia care for the pediatric patient undergoing a kidney transplantation: an educational review

M Voet, EAM Cornelissen… - Pediatric …, 2021 - Wiley Online Library
Living‐donor kidney transplantation is the first choice therapy for children with end‐stage
renal disease and shows good long‐term outcome. Etiology of renal failure, co‐morbidities …

Magnetic solid-phase extraction coupled with LC-MS/MS methods for the simple extraction and rapid determination of sugammadex in human plasma

Y Wang, Y Qu, Y Jiang, Z Li, X Hou, L Yang… - Analytical …, 2024 - pubs.rsc.org
Sugammadex (SUG) is a novel antagonist of neuromuscular blocking agents (NMBAs). The
NMBA rocuronium is usually employed to obtain better surgical conditions in kidney …

Sugammadex: Applications in pediatric critical care

JD Tobias - Journal of Pediatric Intensive Care, 2020 - thieme-connect.com
Sugammadex is a novel pharmacologic agent, which reverses neuromuscular blockade with
a mechanism that differs from acetylcholinesterase inhibitors such as neostigmine. There is …

Retrospective investigation of grafted kidney function after reversal of neuromuscular blockade using neostigmine or sugammadex

R Arslantas, BE Cevik - Transplantation Proceedings, 2019 - Elsevier
Introduction Sugammadex has the steroid-encapsulating effect that reverses neuromuscular
block induced by aminosteroid neuromuscular-blocking agents. Sugammadex can interact …

Sugammadex given for rocuronium-induced neuromuscular blockade in infants: a retrospectıve study

O Ozmete, C Bali, OY Cok, HEE Turk… - Journal of Clinical …, 2016 - Elsevier
Abstract Study Objective To evaluate the efficacy and safety of sugammadex in reversing
profound neuromuscular block induced by rocuronium in infant patients. Design …

Effects of sugammadex plus rocuronium vs neostigmine plus cisatracurium during renal transplantation on graft function: a retrospective, case-control study

M Vargas, P Buonanno, A Sica, E Sabatella… - Transplantation …, 2021 - Elsevier
Background Rocuronium can be used in patients with severe renal failure (creatinine
clearance< 30 mL/min), but the duration of muscle relaxation is longer and results in an …