Large-scale neural recordings call for new insights to link brain and behavior

AE Urai, B Doiron, AM Leifer, AK Churchland - Nature neuroscience, 2022 - nature.com
Neuroscientists today can measure activity from more neurons than ever before, and are
facing the challenge of connecting these brain-wide neural recordings to computation and …

Diffusion decision model: Current issues and history

R Ratcliff, PL Smith, SD Brown, G McKoon - Trends in cognitive sciences, 2016 - cell.com
There is growing interest in diffusion models to represent the cognitive and neural processes
of speeded decision making. Sequential-sampling models like the diffusion model have a …

Geometry of abstract learned knowledge in the hippocampus

EH Nieh, M Schottdorf, NW Freeman, RJ Low… - Nature, 2021 - nature.com
Hippocampal neurons encode physical variables,,,,,–such as space or auditory frequency in
cognitive maps. In addition, functional magnetic resonance imaging studies in humans have …

Where does EEG come from and what does it mean?

MX Cohen - Trends in neurosciences, 2017 - cell.com
Electroencephalography (EEG) has been instrumental in making discoveries about
cognition, brain function, and dysfunction. However, where do EEG signals come from and …

A synaptic threshold mechanism for computing escape decisions

DA Evans, AV Stempel, R Vale, S Ruehle, Y Lefler… - Nature, 2018 - nature.com
Escaping from imminent danger is an instinctive behaviour that is fundamental for survival,
and requires the classification of sensory stimuli as harmless or threatening. The absence of …

Task-dependent changes in the large-scale dynamics and necessity of cortical regions

L Pinto, K Rajan, B DePasquale, SY Thiberge… - Neuron, 2019 - cell.com
Neural activity throughout the cortex is correlated with perceptual decisions, but inactivation
studies suggest that only a small number of areas are necessary for these behaviors. Here …

Context-dependent computation by recurrent dynamics in prefrontal cortex

V Mante, D Sussillo, KV Shenoy, WT Newsome - nature, 2013 - nature.com
Prefrontal cortex is thought to have a fundamental role in flexible, context-dependent
behaviour, but the exact nature of the computations underlying this role remains largely …

Mice alternate between discrete strategies during perceptual decision-making

ZC Ashwood, NA Roy, IR Stone… - Nature …, 2022 - nature.com
Classical models of perceptual decision-making assume that subjects use a single,
consistent strategy to form decisions, or that decision-making strategies evolve slowly over …

The speed-accuracy tradeoff: history, physiology, methodology, and behavior

RP Heitz - Frontiers in neuroscience, 2014 - frontiersin.org
There are few behavioral effects as ubiquitous as the speed-accuracy tradeoff (SAT). From
insects to rodents to primates, the tendency for decision speed to covary with decision …

Perceptual decision making in rodents, monkeys, and humans

TD Hanks, C Summerfield - Neuron, 2017 - cell.com
Perceptual decision making is the process by which animals detect, discriminate, and
categorize information from the senses. Over the past two decades, understanding how …