Malignant melanoma is the most aggressive form of skin cancer. Standard treatment options
include surgery, radiation therapy, systemic chemotherapy, targeted therapy, and …

Importance Melanoma accounts for most of the deaths due to skin cancer. In the past
decade, effective US Food and Drug Administration (FDA)–approved therapies for …

The NCCN Guidelines for Cutaneous Melanoma (termed Melanoma: Cutaneous) provide
multidisciplinary recommendations for diagnostic workup, staging, and treatment of patients …

Malignant melanoma (MM) is the most lethal skin cancer. Despite a 4% reduction in mortality
over the past few years, an increasing number of new diagnosed cases appear each year …

Subversion of immunity by tumors is a crucial step for their development. Dendritic cells
(DCs) are strategic immune cells that orchestrate anti-tumor immune responses but display …

ABSTRACT Indoleamine 2, 3 dioxygenase 1 (IDO1), a leader tryptophan-degrading
enzyme, represents a recognized immune checkpoint molecule. In neoplasia, IDO1 is often …

Background The survival and prognosis of patients are significantly threatened by
cutaneous melanoma (CM), which is a highly aggressive disease. It is therefore crucial to …

Invasive cutaneous melanoma is the most lethal skin cancer, but fortunately, the vast
majority can be surgically treated with wide local excision, and sometimes additionally with …

Numerous epidemiological studies report an increased risk of developing prostate cancer in
patients with melanoma and an increased risk of developing melanoma in patients with …

Early detection is essential for the successful removal of all malignant lesions from the body,
and skin cancer is one of the most widespread cancers globally. In medical image analysis …