Cone snails: A big store of conotoxins for novel drug discovery
Marine drugs have developed rapidly in recent decades. Cone snails, a group of more than
700 species, have always been one of the focuses for new drug discovery. These venomous …
700 species, have always been one of the focuses for new drug discovery. These venomous …
Animal protein toxins: origins and therapeutic applications
N Chen, S Xu, Y Zhang, F Wang - Biophysics reports, 2018 - Springer
Venomous animals on the earth have been found to be valuable resources for the
development of therapeutics. Enzymatic and non-enzymatic proteins and peptides are the …
development of therapeutics. Enzymatic and non-enzymatic proteins and peptides are the …
[HTML][HTML] Prevention, inhibition, and degradation effects of melittin alone and in combination with vancomycin and rifampin against strong biofilm producer strains of …
R Mirzaei, MY Alikhani, CR Arciola, I Sedighi… - Biomedicine & …, 2022 - Elsevier
Methicillin-resistant Staphylococcus epidermidis (MRSE) bacteria are being recognized as
true pathogens as they are able to resist methicillin and commonly form biofilms. Recent …
true pathogens as they are able to resist methicillin and commonly form biofilms. Recent …
Hydrophilic interaction chromatography for the analysis of biopharmaceutical drugs and therapeutic peptides: A review based on the separation characteristics of the …
T Ikegami - Journal of separation science, 2019 - Wiley Online Library
Applications of hydrophilic interaction chromatography for the analysis of biopharmaceutical
drugs, ie, glycosylated proteins represented by monoclonal antibodies are discussed in the …
drugs, ie, glycosylated proteins represented by monoclonal antibodies are discussed in the …
Antibiofilm effect of melittin alone and in combination with conventional antibiotics toward strong biofilm of MDR-MRSA and -Pseudomonas aeruginosa
R Mirzaei, H Esmaeili Gouvarchin Ghaleh… - Frontiers in …, 2023 - frontiersin.org
Introduction Multidrug-resistant (MDR) pathogens are being recognized as a critical threat to
human health if they can form biofilm and, in this sense, biofilm-forming MDR-methicillin …
human health if they can form biofilm and, in this sense, biofilm-forming MDR-methicillin …
Why to study peptides from venomous and poisonous animals?
AN de Oliveira, AM Soares, SL Da Silva - International Journal of Peptide …, 2023 - Springer
Venom and poison peptides are powerful biological weapons and have proven immense
pharmacological potential because of their high binding affinity to a wide range of molecular …
pharmacological potential because of their high binding affinity to a wide range of molecular …
Highly Synergistic Effects of Melittin With Vancomycin and Rifampin Against Vancomycin and Rifampin Resistant Staphylococcus epidermidis
R Mirzaei, MY Alikhani, CR Arciola, I Sedighi… - Frontiers in …, 2022 - frontiersin.org
Methicillin-resistant Staphylococcus epidermidis (MRSE) strains are increasingly emerging
as serious pathogens because they can be resistant to many antibiotics called multidrug …
as serious pathogens because they can be resistant to many antibiotics called multidrug …
Fast killing kinetics, significant therapeutic index, and high stability of melittin-derived antimicrobial peptide
R Akbari, M Hakemi Vala, JM Sabatier… - Amino Acids, 2022 - Springer
The emergence of multidrug-resistant (MDR) bacteria is a major challenge for antimicrobial
chemotherapy. Concerning this issue, antimicrobial peptides (AMPs) have been presented …
chemotherapy. Concerning this issue, antimicrobial peptides (AMPs) have been presented …
Improving bactericidal performance of implant composite coatings by synergism between Melittin and tetracycline
Methicillin resistance Staphylococcus aureus bacteria (MRSA) are serious hazards of bone
implants. The present study was aimed to use the potential synergistic effects of Melittin and …
implants. The present study was aimed to use the potential synergistic effects of Melittin and …
Eradication of vancomycin-resistant Staphylococcus aureus on a mouse model of third-degree burn infection by melittin: an antimicrobial peptide from bee venom
P Bevalian, F Pashaei, R Akbari, KP Bagheri - Toxicon, 2021 - Elsevier
Third-degree burn infections caused by antibiotic-resistant bacteria are of high clinical
concern. Chemical antibiotics are not promising in eradication of bacterial infections. In this …
concern. Chemical antibiotics are not promising in eradication of bacterial infections. In this …