Gadolinium deposition in the brain: summary of evidence and recommendations

V Gulani, F Calamante, FG Shellock, E Kanal… - The Lancet …, 2017 - thelancet.com
Emerging evidence has linked MRI signal changes in deep nuclei of the brain with repeated
administration of gadolinium-based contrast agents. Gadolinium deposits have been …

Gadolinium retention: a research roadmap from the 2018 NIH/ACR/RSNA workshop on gadolinium chelates

RJ McDonald, D Levine, J Weinreb, E Kanal… - Radiology, 2018 - pubs.rsna.org
Gadolinium-based contrast agents (GBCAs) have revolutionized MRI, enabling physicians
to obtain crucial life-saving medical information that often cannot be obtained with other …

Macrocyclic and other non–group 1 gadolinium contrast agents deposit low levels of gadolinium in brain and bone tissue: preliminary results from 9 patients with …

N Murata, LF Gonzalez-Cuyar, K Murata… - Investigative …, 2016 - journals.lww.com
Objective The purpose of this study was to determine whether gadolinium (Gd) is deposited
in brain and bone tissues in patients receiving only non–Group 1 agents, either macrocyclic …

Gadolinium-based contrast agent accumulation and toxicity: an update

J Ramalho, RC Semelka, M Ramalho… - American Journal …, 2016 - Am Soc Neuroradiology
In current practice, gadolinium-based contrast agents have been considered safe when
used at clinically recommended doses in patients without severe renal insufficiency. The …

[HTML][HTML] 25 years of contrast-enhanced MRI: developments, current challenges and future perspectives

J Lohrke, T Frenzel, J Endrikat, FC Alves, TM Grist… - Advances in …, 2016 - Springer
In 1988, the first contrast agent specifically designed for magnetic resonance imaging (MRI),
gadopentetate dimeglumine (Magnevist®), became available for clinical use. Since then, a …

[HTML][HTML] Gadolinium deposition in the brain: current updates

JW Choi, WJ Moon - Korean journal of radiology, 2019 - synapse.koreamed.org
Gadolinium-based contrast agents (GBCAs) are commonly used for enhancement in MR
imaging and have long been considered safe when administered at recommended doses …

[HTML][HTML] T1-weighted hypersignal in the deep cerebellar nuclei after repeated administrations of gadolinium-based contrast agents in healthy rats: difference between …

P Robert, S Lehericy, S Grand, X Violas… - Investigative …, 2015 - journals.lww.com
Objectives To prospectively compare in healthy rats the effect of multiple injections of
macrocyclic (gadoterate meglumine) and linear (gadodiamide) gadolinium-based contrast …

Residual or retained gadolinium: practical implications for radiologists and our patients

E Kanal, MF Tweedle - Radiology, 2015 - pubs.rsna.org
Residual or Retained Gadolinium: Practical Implications for Radiologists and Our Patients |
Radiology RSNA "skipMainNavigation" closeDrawerMenuopenDrawerMenu Home Journals All …

[HTML][HTML] Gadolinium: pharmacokinetics and toxicity in humans and laboratory animals following contrast agent administration

J Davies, P Siebenhandl-Wolff, F Tranquart… - Archives of …, 2022 - Springer
Gadolinium-based contrast agents (GBCAs) have transformed magnetic resonance imaging
(MRI) by facilitating the use of contrast-enhanced MRI to allow vital clinical diagnosis in a …

[HTML][HTML] The presence of the gadolinium-based contrast agent depositions in the brain and symptoms of gadolinium neurotoxicity-A systematic review

C Olchowy, K Cebulski, M Łasecki, R Chaber… - PloS one, 2017 - journals.plos.org
Background and purpose Gadolinium based contrast agents (GBCAs) are widely used in
magnetic resonance imaging, but recently, high signal intensity in the cerebellum structures …