The Outstanding Chemodiversity of Marine-Derived Talaromyces

R Nicoletti, R Bellavita, A Falanga - Biomolecules, 2023 - mdpi.com
Fungi in the genus Talaromyces occur in every environment in both terrestrial and marine
contexts, where they have been quite frequently found in association with plants and …

Investigating the hepatoprotective potentiality of marine-derived steroids as promising inhibitors of liver fibrosis

MA Tammam, F Pereira, O Aly, M Sebak, YM Diab… - RSC …, 2023 - pubs.rsc.org
It has been reported that organic extracts derived from soft corals belonging to the genus
Sarcophyton have exhibited a wide range of therapeutic characteristics. Based on …

[HTML][HTML] A review on the synthesis and application of naphthoquinone-based drugs

J Khan, A Rani, M Aslam, G Pandey, BN Pant - Results in Chemistry, 2023 - Elsevier
Naphthoquinones are secondary plant metabolites that are used to treat a variety of human
ailments in traditional medicine. In light of this, the synthesis of derivatives of …

Exploring the antioxidant, anticancer and antimicrobial potential of Amaranthus viridis L. collected from Fayoum depression: Phytochemical, and biological aspects

MS Fouad, MA Ghareeb, AA Hamed, EA Aidy… - South African Journal of …, 2024 - Elsevier
Amaranthus viridis (AV) is an invasive weed designated for natural antioxidants. In the
current endeavor, A. viridis aerial parts and soil samples were collected from six districts of …

Naphthoquinone Derivatives from Angustimassarina populi CF-097565 Display Anti-Tumour Activity in 3D Cultures of Breast Cancer Cells

TA Mackenzie, F Reyes, M Martínez… - Molecules, 2024 - mdpi.com
Cancer is one of the leading causes of death worldwide, with breast cancer being the
second cause of cancer-related mortality among women. Natural Products (NPs) are one of …

Neuroprotective evaluation of diospyrin against drug-induced Alzheimer's disease

A Alam, G Ali, A Nawaz, TS AlOmar, A Rauf, M Ayaz… - Fitoterapia, 2023 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disease linked to memory
impairment. A current investigation was performed to assess the neuroprotective effect of …

Green synthesis, antimycobacterial evaluation and molecular docking studies of novel 2, 3-dihydro-1H-pyrazol-4-ylnaphthalene-1, 4-diones

DP Hiwarale, WB Chandane, SM Deshmukh… - Journal of Molecular …, 2023 - Elsevier
Abstract A novel series of 2, 3-dihydro-1H-pyrazol-4-ylnaphthalene-1, 4-diones is
synthesized via one-pot, multi-component condensation of ethyl acetoacetate, 4 …

Cephalostatins and ritterazines: Distinctive dimeric marine-derived steroidal pyrazine alkaloids with intriguing anticancer activities

MA Tammam, MIG El-Din, A Aouidate… - Bioorganic …, 2024 - Elsevier
Cephalostatins and ritterazines represent fascinating classes of dimeric marine derived
steroidal alkaloids with unique chemical structures and promising biological activities …

Computer-aided discovery of novel SmDHODH inhibitors for schistosomiasis therapy: Ligand-based drug design, molecular docking, molecular dynamic simulations …

SC Ja'afaru, A Uzairu, S Hossain… - PLOS Neglected …, 2024 - journals.plos.org
Schistosomiasis, also known as bilharzia or snail fever, is a tropical parasitic disease
resulting from flatworms of the Schistosoma genus. This often overlooked disease has …

Recent advances in the discovery, biosynthesis, and therapeutic potential of isocoumarins derived from fungi: a comprehensive update

MA Tammam, MIG El-Din, A Abood, A El-Demerdash - RSC advances, 2023 - pubs.rsc.org
Microorganisms still remain the main hotspots in the global drug discovery avenue. In
particular, fungi are highly prolific producers of vast structurally diverse specialized …