GK BertDTA: a graph representation learning and semantic embedding-based framework for drug-target affinity prediction

X Qiu, H Wang, X Tan, Z Fang - Computers in Biology and Medicine, 2024 - Elsevier
Developing new drugs is costly, time-consuming, and risky. Drug-target affinity (DTA),
indicating the binding capability between drugs and target proteins, is a crucial indicator for …

Advanced Molecular Docking Approach to Simulate Intermolecular Interaction and Binding Affinity Energy of Four Key Bio-Compounds Against Angiotensin …

MS Bensaad, HJ Banjer, KJ Alzahrani… - Journal of Biobased …, 2023 - ingentaconnect.com
The scientific community has been mobilized in recent years at the international level to find
concrete solution, in order to elaborate vaccines against Covid-19 with less side-effects and …

[PDF][PDF] Computational Tools and Data Integration to Accelerate Vaccine Development: Challenges, Opportunities, and Future Directions

LN Anderson, CT Hoyt, J Zucker, JR Teuton… - osf.io
The development of effective vaccines is crucial for combating current and emerging
pathogens. Despite significant advances in the field of vaccine development there remain …

[PDF][PDF] Feed Forward Neural Network-Based Approaches for Vaccine Target Identification: Implementation and Insights

S Verma, M Garg, R Gandotra, P Mahajan, NP Vidhu… - osf.io
Vaccine development relies heavily on the identification of appropriate antigen targets to
induce robust immune responses. Traditional methods for vaccine target identification often …