Numerous proteins, including cytokines and chemokines, enzymes and enzyme inhibitors,
extracellular matrix proteins, and membrane receptors, bind heparin. Although they are …

Glycosaminoglycans are natural heteropolysaccharides that are present in every
mammalian tissue. They are composed of repeating disaccharide units that consist of either …

Proteoglycans are widely expressed in animal cells. Interactions between negatively
charged glycosaminoglycan chains and molecules such as growth factors are essential for …

Proteoglycans are glycosylated proteins which have cova‐lently attached highly anionic
glycosaminoglycans. Many forms of proteoglycans are present In virtually all extracellular …

Polyclonal antibodies were prepared against the period gene product, which influences
biological rhythms in D. melanogaster, by using small synthetic peptides from the per …

Glycosarninoglycans (GAGs) play an intricate role in the extracellular matrix (ECM), not only
as soluble components and polyelectrolytes, but also by specific interactions with growth …

Heparan sulfate proteoglycans are ubiquitously found at the cell surface and extracellular
matrix in all the animal species. This review will focus on the structural characteristics of the …

Adeno-associated viruses (AAV) are ubiquitous in the human population (> 90% of adults
are seropositive) but have never been implicated as the cause of any disease. They were …

Heparanase is an endoglucuronidase that cleaves heparan sulfate chains of proteoglycans.
In many malignancies, high heparanase expression and activity correlate with an …

Cell-penetrating peptides (CPPs) are cationic peptides which, when linked to genes,
proteins, or nanoparticles, facilitate the transport of these entities across the cell membrane …