Acute myeloid leukemia with the t (8; 21) translocation: clinical consequences and biological implications
H Reikvam, KJ Hatfield, AO Kittang… - BioMed Research …, 2011 - Wiley Online Library
The t (8; 21) abnormality occurs in a minority of acute myeloid leukemia (AML) patients. The
translocation results in an in‐frame fusion of two genes, resulting in a fusion protein of one N …
translocation results in an in‐frame fusion of two genes, resulting in a fusion protein of one N …
Subcellular localization of the Schlafen protein family
B Neumann, L Zhao, K Murphy, TJ Gonda - Biochemical and biophysical …, 2008 - Elsevier
Although the first members of the Schlafen gene family were first described almost 10 years
ago, the precise molecular/biochemical functions of the proteins they encode still remain …
ago, the precise molecular/biochemical functions of the proteins they encode still remain …
The Leukemia-Specific Fusion Gene ETV6/RUNX1 Perturbs Distinct Key Biological Functions Primarily by Gene Repression
G Fuka, M Kauer, R Kofler, OA Haas… - PloS one, 2011 - journals.plos.org
Background ETV6/RUNX1 (E/R)(also known as TEL/AML1) is the most frequent gene fusion
in childhood acute lymphoblastic leukemia (ALL) and also most likely the crucial factor for …
in childhood acute lymphoblastic leukemia (ALL) and also most likely the crucial factor for …
Down-regulation of microRNAs 222/221 in acute myelogenous leukemia with deranged core-binding factor subunits
M Brioschi, J Fischer, R Cairoli, S Rossetti, L Pezzetti… - Neoplasia, 2010 - Elsevier
Core-binding factor leukemia (CBFL) is a subgroup of acutemyeloid leukemia (AML)
characterized by genetic mutations involving the subunits of the core-binding factor (CBF) …
characterized by genetic mutations involving the subunits of the core-binding factor (CBF) …
Towards integrated oncogenic marker recognition through mutual information‐based statistically significant feature extraction: an association rule mining based study …
Background Marker detection is an important task in complex disease studies. Here we
provide an association rule mining (ARM) based approach for identifying integrated markers …
provide an association rule mining (ARM) based approach for identifying integrated markers …
Novel RNA-binding properties of the MTG chromatin regulatory proteins
S Rossetti, L van Unen, N Sacchi… - BMC Molecular Biology, 2008 - Springer
Background The myeloid translocation gene (MTG) proteins are non-DNA-binding
transcriptional regulators capable of interacting with chromatin modifying proteins. As a …
transcriptional regulators capable of interacting with chromatin modifying proteins. As a …
[PDF][PDF] Epigenetics and leukemia: unraveling oncogenic processes in the BLV ovine model
M Merimi, Y Ozkan, Y Cleuter, P Griebel… - … Biosci (Schol Ed), 2009 - article.imrpress.com
[Frontiers in Bioscience S1, 154-163, June 1, 2009] 154 Epigenetics and leukemia: unraveling
oncogenic processes in the BLV ovin Page 1 [Frontiers in Bioscience S1, 154-163, June 1, 2009] …
oncogenic processes in the BLV ovin Page 1 [Frontiers in Bioscience S1, 154-163, June 1, 2009] …
[图书][B] Microarray Bioinformatics and Applications in Oncology
J Peeters - 2008 - repub.eur.nl
Bioinformatics' is one of the newest fields of biological research, and should be viewed
broadly as the use of mathematical, statistical, and computational methods for the …
broadly as the use of mathematical, statistical, and computational methods for the …