Skin wounds greatly affect the global healthcare system, creating a substantial burden on
the economy and society. Moreover, the situation is exacerbated by low healing rates, which …

Wound healing is a complex, dynamic process supported by a myriad of cellular events that
must be tightly coordinated to efficiently repair damaged tissue. Derangement in wound …

The skin is a complex organ that has devised numerous strategies, such as physical,
chemical, and microbiological barriers, to protect the host from external insults. In addition …

Experimental work of the last two decades has revealed the general steps of the wound
healing process. This complex network has been organized in three sequential and …

The process of healing a wound is multifaceted and organized that needs the organization
and support of countless biological activities to achieve effective repair of damage …

Mast cells (MCs), apart from their classic role in allergy, contribute to a number of biologic
processes including wound healing. In particular, two aspects of their histologic distribution …

A diverse range of normal flora populates the human skin and numbers are relatively
different between individuals and parts of the skin. Humans and normal flora have formed a …

The treatment of chronic wounds still challenges modern medicine because of these
wounds' heterogenic pathophysiology. Processes such as inflammation, ischemia and …

Wound healing is a dynamic process which involves stages of hemostasis, inflammation,
proliferation and remodeling. Any error in this process results in abnormal wound healing …

Macrophages regulate cutaneous wound healing by immune surveillance, tissue repair and
remodelling. The depletion of dermal macrophages during the early and middle stages of …