Oxidative stress in human pathology and aging: molecular mechanisms and perspectives

YA Hajam, R Rani, SY Ganie, TA Sheikh, D Javaid… - Cells, 2022 - mdpi.com
Reactive oxygen and nitrogen species (RONS) are generated through various endogenous
and exogenous processes; however, they are neutralized by enzymatic and non-enzymatic …

Oxidative stress in chronic kidney disease

K Daenen, A Andries, D Mekahli, A Van Schepdael… - Pediatric …, 2019 - Springer
Oxidative stress (OS), defined as disturbances in the pro-/antioxidant balance, is harmful to
cells due to the excessive generation of highly reactive oxygen (ROS) and nitrogen (RNS) …

Inflammation and oxidative stress in chronic kidney disease—potential therapeutic role of minerals, vitamins and plant-derived metabolites

SF Rapa, BR Di Iorio, P Campiglia, A Heidland… - International journal of …, 2019 - mdpi.com
Chronic kidney disease (CKD) is a debilitating pathology with various causal factors,
culminating in end stage renal disease (ESRD) requiring dialysis or kidney transplantation …

Oxidative stress in the pathogenesis and evolution of chronic kidney disease: untangling Ariadne's thread

A Duni, V Liakopoulos, S Roumeliotis… - International journal of …, 2019 - mdpi.com
Amplification of oxidative stress is present since the early stages of chronic kidney disease
(CKD), holding a key position in the pathogenesis of renal failure. Induction of renal pro …

The role of antioxidants in the chemistry of oxidative stress: A review

AM Pisoschi, A Pop - European journal of medicinal chemistry, 2015 - Elsevier
Abstract This Review Article is focused on the action of the reactive oxygenated species in
inducing oxidative injury of the lipid membrane components, as well as on the ability of …

Oxidative stress in the pathophysiology of kidney disease: implications for noninvasive monitoring and identification of biomarkers

M Gyurászová, R Gurecká, J Bábíčková… - … medicine and cellular …, 2020 - Wiley Online Library
Kidney disease represents a serious global health problem. One of the main concerns is its
late diagnosis, only feasible in a progressed disease state. The lack of a clinical …

Role of resveratrol in regulation of cellular defense systems against oxidative stress

VL Truong, M Jun, WS Jeong - Biofactors, 2018 - Wiley Online Library
Resveratrol, a natural polyphenolic compound, is found in various kinds of fruits, plants, and
their commercial products such as red wine. It has been demonstrated to exhibit a variety of …

[HTML][HTML] The systemic nature of CKD

C Zoccali, R Vanholder, ZA Massy, A Ortiz… - Nature Reviews …, 2017 - nature.com
The accurate definition and staging of chronic kidney disease (CKD) is one of the major
achievements of modern nephrology. Intensive research is now being undertaken to unravel …

Engineering antioxidative cascade metal-phenolic nanozymes for alleviating oxidative stress during extracorporeal blood purification

Z Wei, G Peng, Y Zhao, S Chen, R Wang, H Mao… - ACS …, 2022 - ACS Publications
Oxidative stress is a compelling risk factor in chronic kidney diseases and is further
aggravated for individuals during extracorporeal blood purification, ultimately leading to …

Oxidative stress in hemodialysis patients: a review of the literature

V Liakopoulos, S Roumeliotis, X Gorny… - Oxidative medicine …, 2017 - Wiley Online Library
Hemodialysis (HD) patients are at high risk for all‐cause mortality and cardiovascular
events. In addition to traditional risk factors, excessive oxidative stress (OS) and chronic …