Mobile genetic elements associated with antimicrobial resistance

SR Partridge, SM Kwong, N Firth… - Clinical microbiology …, 2018 - Am Soc Microbiol
Strains of bacteria resistant to antibiotics, particularly those that are multiresistant, are an
increasing major health care problem around the world. It is now abundantly clear that both …

Plasmid transfer by conjugation in Gram-negative bacteria: from the cellular to the community level

C Virolle, K Goldlust, S Djermoun, S Bigot, C Lesterlin - Genes, 2020 - mdpi.com
Bacterial conjugation, also referred to as bacterial sex, is a major horizontal gene transfer
mechanism through which DNA is transferred from a donor to a recipient bacterium by direct …

Engineered bacterial orthogonal DNA replication system for continuous evolution

R Tian, R Zhao, H Guo, K Yan, C Wang, C Lu… - Nature Chemical …, 2023 - nature.com
Continuous evolution can generate biomolecules for synthetic biology and enable
evolutionary investigation. The orthogonal DNA replication system (OrthoRep) in yeast can …

Fitness costs of plasmids: a limit to plasmid transmission

A San Millan, RC MacLean - Microbiology spectrum, 2017 - Am Soc Microbiol
Plasmids mediate the horizontal transmission of genetic information between bacteria,
facilitating their adaptation to multiple environmental conditions. An especially important …

Short prokaryotic Argonautes provide defence against incoming mobile genetic elements through NAD+ depletion

M Zaremba, D Dakineviciene, E Golovinas… - Nature …, 2022 - nature.com
Argonaute (Ago) proteins are found in all three domains of life. The so-called long Agos are
composed of four major domains (N, PAZ, MID and PIWI) and contribute to RNA silencing in …

Plasmid evolution in carbapenemase‐producing Enterobacteriaceae: a review

K Kopotsa, J Osei Sekyere… - Annals of the New York …, 2019 - Wiley Online Library
Carbapenem‐resistant Enterobacteriaceae (CRE) have been listed by the WHO as high‐
priority pathogens owing to their high association with mortalities and morbidities …

Recombinant protein expression in Escherichia coli: advances and challenges

GL Rosano, EA Ceccarelli - Frontiers in microbiology, 2014 - frontiersin.org
Escherichia coli is one of the organisms of choice for the production of recombinant proteins.
Its use as a cell factory is well-established and it has become the most popular expression …

Genomics of microbial plasmids: classification and identification based on replication and transfer systems and host taxonomy

M Shintani, ZK Sanchez, K Kimbara - Frontiers in microbiology, 2015 - frontiersin.org
Plasmids are important “vehicles” for the communication of genetic information between
bacteria. The exchange of plasmids transmits pathogenically and environmentally relevant …

[图书][B] Processes of life: Essays in the philosophy of biology

J Dupré - 2012 - books.google.com
John Dupré explores recent revolutionary developments in biology and considers their
relevance for our understanding of human nature and human society. Epigenetics and …

Universal whole-sequence-based plasmid typing and its utility to prediction of host range and epidemiological surveillance

J Robertson, K Bessonov, J Schonfeld… - Microbial …, 2020 - microbiologyresearch.org
Bacterial plasmids play a large role in allowing bacteria to adapt to changing environments
and can pose a significant risk to human health if they confer virulence and antimicrobial …