Review of key issues and potential strategies in bio-degradation of polyolefins
D Kong, L Wang, Y Yuan, W Xia, Z Liu, M Shi… - Bioresource …, 2024 - Elsevier
Polyolefins are the most widely used plastic product and a major contributor to white
pollution. Currently, studies on polyolefin degradation systems are mainly focused on …
pollution. Currently, studies on polyolefin degradation systems are mainly focused on …
Solar-powered P450 catalysis: Engineering electron transfer pathways from photosynthesis to P450s
B Agustinus, EMJ Gillam - Journal of Inorganic Biochemistry, 2023 - Elsevier
With the increasing focus on green chemistry, biocatalysis is becoming more widely used in
the pharmaceutical and other chemical industries for sustainable production of high value …
the pharmaceutical and other chemical industries for sustainable production of high value …
Selective carbon-hydrogen bond hydroxylation using an engineered cytochrome P450 peroxygenase
The cytochrome P450 enzyme CYP102A1 (P450BM3) is a versatile monooxygenase
enzyme which has been adapted and engineered for multiple applications in chemical …
enzyme which has been adapted and engineered for multiple applications in chemical …
Engineering Peroxygenase Activity into Cytochrome P450 Monooxygenases through Modification of the Oxygen Binding Region
MN Podgorski, J Akter, LR Churchman, JB Bruning… - ACS …, 2024 - ACS Publications
Cytochrome P450 enzymes (CYPs) are biocatalysts for the generation of fine chemicals
including natural products, drug metabolites, and flavor and fragrance compounds …
including natural products, drug metabolites, and flavor and fragrance compounds …
Efficient regio-and stereo-selective C–H bond hydroxylation of steroids using an engineered heme-thiolate peroxygenase biocatalyst
A crucial reaction in chemical synthesis is the activation of unactivated carbon–hydrogen
bonds in complex molecules. We demonstrate the regio-and stereo-selective hydroxlation of …
bonds in complex molecules. We demonstrate the regio-and stereo-selective hydroxlation of …
An In Crystallo Reaction with an Engineered Cytochrome P450 Peroxygenase
The cytochrome P450 monooxygenases (CYPs) are a class of heme‐thiolate enzymes that
insert oxygen into unactivated C− H bonds. These enzymes can be converted into …
insert oxygen into unactivated C− H bonds. These enzymes can be converted into …
[HTML][HTML] Characterisation of the heme aqua-ligand coordination environment in an engineered peroxygenase cytochrome P450 variant
MN Podgorski, JHZ Lee, JS Harbort… - Journal of Inorganic …, 2023 - Elsevier
The cytochrome P450 enzymes (CYPs) are heme-thiolate monooxygenases that catalyse
the insertion of an oxygen atom into the C–H bonds of organic molecules. In most CYPs, the …
the insertion of an oxygen atom into the C–H bonds of organic molecules. In most CYPs, the …
The catalytic activity and structure of the lipid metabolizing CYP124 cytochrome P450 enzyme from Mycobacterium marinum
The CYP124 family of cytochrome P450 enzymes, as exemplified by CYP124A1 from
Mycobacterium tuberculosis, is involved in the metabolism of methyl branched lipids and …
Mycobacterium tuberculosis, is involved in the metabolism of methyl branched lipids and …
Alternative electron sources for cytochrome P450s catalytic cycle: biosensing and biosynthetic application
VV Shumyantseva, PI Koroleva, TV Bulko… - Processes, 2023 - mdpi.com
The functional significance of cytochrome P450s (CYP) enzymes is their ability to catalyze
the biotransformation of xenobiotics and endogenous compounds. P450 enzymes catalyze …
the biotransformation of xenobiotics and endogenous compounds. P450 enzymes catalyze …
Cytochrome P450-catalyzed oxidation of halogen-containing substrates
T Coleman, MN Podgorski, ML Doyle… - Journal of Inorganic …, 2023 - Elsevier
Cytochrome P450 (CYP) enzymes are heme-thiolate monooxygenases which catalyze the
oxidation of aliphatic and aromatic CH bonds and other reactions. The oxidation of halogens …
oxidation of aliphatic and aromatic CH bonds and other reactions. The oxidation of halogens …