Association between vaccination status and mortality among intubated patients with COVID-19–related acute respiratory distress syndrome
E Grapsa, G Adamos, I Andrianopoulos… - JAMA network …, 2022 - jamanetwork.com
Importance Although vaccination substantially reduces the risk of severe COVID-19, it is yet
unknown whether vaccinated patients who develop COVID-19 and require invasive …
unknown whether vaccinated patients who develop COVID-19 and require invasive …
[PDF][PDF] COVID-19 Compared with Other Viral Diseases: Novelties, Progress, and Challenges.
L Wang, CA Alexander - Electronic Journal of General Medicine, 2021 - ejgm.co.uk
Accepted: 4 Aug. 2020 COVID-19 is a newly discovered, highly infectious disease and has
rapidly spread into at least 213 countries as a pandemic. This paper is a comprehensive …
rapidly spread into at least 213 countries as a pandemic. This paper is a comprehensive …
Postoperative acute respiratory distress syndrome in randomized controlled trials
Background Acute respiratory distress syndrome is a potentially fatal postoperative
complication. We aimed to estimate temporal trends of the representation of patients with …
complication. We aimed to estimate temporal trends of the representation of patients with …
Identification of persistent and resolving subphenotypes of acute hypoxemic respiratory failure in two independent cohorts
NA Sathe, LR Zelnick, C Mikacenic, ED Morrell… - Critical Care, 2021 - Springer
Background Acute hypoxemic respiratory failure (HRF) is associated with high morbidity and
mortality, but its heterogeneity challenges the identification of effective therapies. Defining …
mortality, but its heterogeneity challenges the identification of effective therapies. Defining …
Rapidly improving acute respiratory distress syndrome in COVID-19: a multi-centre observational study
E Gavrielatou, K Vaporidi, V Tsolaki, N Tserlikakis… - Respiratory …, 2022 - Springer
Background Before the pandemic of coronavirus disease (COVID-19), rapidly improving
acute respiratory distress syndrome (ARDS), mostly defined by early extubation, had been …
acute respiratory distress syndrome (ARDS), mostly defined by early extubation, had been …
Development and External Validation of Models to Predict Persistent Hypoxemic Respiratory Failure for Clinical Trial Enrichment
NA Sathe, LR Zelnick, ED Morrell… - Critical care …, 2024 - journals.lww.com
OBJECTIVES: Improving the efficiency of clinical trials in acute hypoxemic respiratory failure
(HRF) depends on enrichment strategies that minimize enrollment of patients who quickly …
(HRF) depends on enrichment strategies that minimize enrollment of patients who quickly …
Rapidly improving ARDS differs clinically and biologically from persistent ARDS
PL Valda Toro, A Willmore, NE Wu, KL Delucchi… - Critical Care, 2024 - Springer
Background Rapidly improving acute respiratory distress syndrome (RIARDS) is an
increasingly appreciated subgroup of ARDS in which hypoxemia improves within 24 h after …
increasingly appreciated subgroup of ARDS in which hypoxemia improves within 24 h after …
Temporal trends of outcomes of neutropenic patients with ARDS enrolled in therapeutic clinical trials
Dear Editor, Outcomes of critically ill patients with neutropenia (including those with acute
respiratory distress syndrome (ARDS)) improve over time, as suggested by data from …
respiratory distress syndrome (ARDS)) improve over time, as suggested by data from …
Prolonged mechanical ventilation in acute respiratory distress syndrome
I Andrianopoulos, VG Giannakoulis, E Papoutsi… - Shock, 2023 - journals.lww.com
Purpose Trajectory of acute respiratory distress syndrome (ARDS) spans from rapidly
improving cases to cases receiving prolonged mechanical ventilation (PMV). We attempted …
improving cases to cases receiving prolonged mechanical ventilation (PMV). We attempted …
Innovation in Enrichment: Is Persistence Enough?
EJ Schenck, II Siempos - Critical Care Medicine, 2024 - journals.lww.com
Clinical trials targeting patients who receive mechanical ventilation often fail (1). There are
numerous causes of this failure, from unmodifiable patient characteristics resulting in poor …
numerous causes of this failure, from unmodifiable patient characteristics resulting in poor …