Some remarks on protein attribute prediction and pseudo amino acid composition

KC Chou - Journal of theoretical biology, 2011 - Elsevier
With the accomplishment of human genome sequencing, the number of sequence-known
proteins has increased explosively. In contrast, the pace is much slower in determining their …

A survey on methods for predicting polyadenylation sites from DNA sequences, bulk RNA-seq, and single-cell RNA-seq

W Ye, Q Lian, C Ye, X Wu - Genomics, Proteomics & …, 2023 - academic.oup.com
Alternative polyadenylation (APA) plays important roles in modulating mRNA stability,
translation, and subcellular localization, and contributes extensively to shaping eukaryotic …

[HTML][HTML] Cell-PLoc 2.0: an improved package of web-servers for predicting subcellular localization of proteins in various organisms

KC Chou, HB Shen - Natural Science, 2010 - scirp.org
Cell-PLoc 2.0 is a package of web-servers evolved from Cell-PLoc (Chou, KC & Shen, HB,
Nature Protocols, 2008, 2: 153-162) by a top-down approach to improve the power for …

AFP-Pred: A random forest approach for predicting antifreeze proteins from sequence-derived properties

KK Kandaswamy, KC Chou, T Martinetz… - Journal of theoretical …, 2011 - Elsevier
Some creatures living in extremely low temperatures can produce some special materials
called “antifreeze proteins”(AFPs), which can prevent the cell and body fluids from freezing …

Identifying bacterial virulent proteins by fusing a set of classifiers based on variants of Chou's pseudo amino acid composition and on evolutionary information

L Nanni, A Lumini, D Gupta… - IEEE/ACM Transactions on …, 2011 - ieeexplore.ieee.org
The availability of a reliable prediction method for prediction of bacterial virulent proteins has
several important applications in research efforts targeted aimed at finding novel drug …

iLoc-Gpos: a multi-layer classifier for predicting the subcellular localization of singleplex and multiplex Gram-positive bacterial proteins

ZC Wu, X Xiao, KC Chou - Protein and peptide letters, 2012 - ingentaconnect.com
By introducing the “multi-layer scale”, as well as hybridizing the information of gene ontology
and the sequential evolution information, a novel predictor, called iLoc-Gpos, has been …

Alternative polyadenylation and gene expression regulation in plants

D Xing, QQ Li - Wiley Interdisciplinary Reviews: RNA, 2011 - Wiley Online Library
Functioning as an essential step of pre‐mRNA processing, polyadenylation has been
realized in recent years to play an important regulatory role during eukaryotic gene …

Identify Golgi protein types with modified mahalanobis discriminant algorithm and pseudo amino acid composition

H Ding, L Liu, FB Guo, J Huang… - Protein and peptide …, 2011 - ingentaconnect.com
The Golgi apparatus is an important eukaryotic organelle. Successful prediction of Golgi
protein types can provide valuable information for elucidating protein functions involved in …

DeepPolyA: a convolutional neural network approach for polyadenylation site prediction

X Gao, J Zhang, Z Wei, H Hakonarson - IEEE Access, 2018 - ieeexplore.ieee.org
Polyadenylation (Poly (A)) plays crucial roles in gene regulation, especially in messenger
RNA metabolism, protein diversification, and protein localization. Accurate prediction of …

Poly (A) motif prediction using spectral latent features from human DNA sequences

B Xie, BR Jankovic, VB Bajic, L Song, X Gao - Bioinformatics, 2013 - academic.oup.com
Motivation: Polyadenylation is the addition of a poly (A) tail to an RNA molecule. Identifying
DNA sequence motifs that signal the addition of poly (A) tails is essential to improved …