The need for better antifungal therapy is commonly accepted in view of the high mortality
rates associated with systemic infections, the low number of available antifungal classes …

The composition of the microbiota is the focus of many recent publications describing the
effects of the microbiota on host health. In recent years, research has progressed further …

Filamentous fungal pathogens have evolved diverse strategies to infect a variety of hosts
including plants and insects. The dynamic infection process requires rapid and fine-tuning …

With the increasing morbidity and mortality of invasive fungal infections and the emergence
of severe antifungal drug resistance, new drug targets and novel antifungal agents are …

Half a century after the introduction of Amphotericin B the management of cryptococcosis
remains unsatisfactory. The disease, caused primarily by the two fungal species …

Invasive fungal infections (particularly candidiasis) are emerging as severe infectious
diseases worldwide. Because of serious antifungal drug resistance, therapeutic efficacy of …

Post-translational modifications (PTMs) change the structure and function of proteins and
regulate a diverse array of biological processes. Fungal pathogens rely on PTMs to …

Cryptococcus neoformans is an opportunistic fungal pathogen that causes life-threatening
meningitis primarily in immunocompromised individuals. In order to survive and proliferate …

The emergence of drug-resistant fungi poses a continuously increasing threat to human
health. Despite advances in preventive care and diagnostics, resistant fungi continue to …

The pathogenic species of Cryptococcus are a major cause of mortality owing to severe
infections in immunocompromised as well as immunocompetent individuals. Although …