The Epidemiology and Pathogenesis and Treatment of Pseudomonas aeruginosa Infections: An Update
D Reynolds, M Kollef - Drugs, 2021 - Springer
Pseudomonas aeruginosa is a Gram-negative bacterial pathogen that is a common cause of
nosocomial infections, particularly pneumonia, infection in immunocompromised hosts, and …
nosocomial infections, particularly pneumonia, infection in immunocompromised hosts, and …
The Japanese clinical practice guidelines for management of sepsis and septic shock 2020 (J-SSCG 2020)
M Egi, H Ogura, T Yatabe, K Atagi, S Inoue, T Iba… - Journal of intensive …, 2021 - Springer
Abstract The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic
Shock 2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis …
Shock 2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis …
International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia: Guidelines for the …
A Torres, MS Niederman, J Chastre… - European …, 2017 - Eur Respiratory Soc
The most recent European guidelines and task force reports on hospital-acquired
pneumonia (HAP) and ventilator-associated pneumonia (VAP) were published almost 10 …
pneumonia (HAP) and ventilator-associated pneumonia (VAP) were published almost 10 …
RESTORE-IMI 1: a multicenter, randomized, double-blind trial comparing efficacy and safety of imipenem/relebactam vs colistin plus imipenem in patients with …
J Motsch, C Murta de Oliveira, V Stus… - Clinical Infectious …, 2020 - academic.oup.com
Background The β-lactamase inhibitor relebactam can restore imipenem activity against
imipenem-nonsusceptible gram-negative pathogens. We evaluated imipenem/relebactam …
imipenem-nonsusceptible gram-negative pathogens. We evaluated imipenem/relebactam …
Optimization of the treatment with beta-lactam antibiotics in critically ill patients—guidelines from the French Society of Pharmacology and Therapeutics (Société …
R Guilhaumou, S Benaboud, Y Bennis… - Critical Care, 2019 - Springer
Background Beta-lactam antibiotics (βLA) are the most commonly used antibiotics in the
intensive care unit (ICU). ICU patients present many pathophysiological features that cause …
intensive care unit (ICU). ICU patients present many pathophysiological features that cause …
Timing of antibiotic therapy in the ICU
Severe or life threatening infections are common among patients in the intensive care unit
(ICU). Most infections in the ICU are bacterial or fungal in origin and require antimicrobial …
(ICU). Most infections in the ICU are bacterial or fungal in origin and require antimicrobial …
Update of the treatment of nosocomial pneumonia in the ICU
R Zaragoza, P Vidal-Cortés, G Aguilar, M Borges… - Critical Care, 2020 - Springer
In accordance with the recommendations of, amongst others, the Surviving Sepsis
Campaign and the recently published European treatment guidelines for hospital-acquired …
Campaign and the recently published European treatment guidelines for hospital-acquired …
Rationalizing antimicrobial therapy in the ICU: a narrative review
The massive consumption of antibiotics in the ICU is responsible for substantial ecological
side effects that promote the dissemination of multidrug-resistant bacteria (MDRB) in this …
side effects that promote the dissemination of multidrug-resistant bacteria (MDRB) in this …
Ceftolozane–tazobactam versus meropenem for treatment of nosocomial pneumonia (ASPECT-NP): a randomised, controlled, double-blind, phase 3, non-inferiority …
MH Kollef, M Nováček, Ü Kivistik… - The Lancet Infectious …, 2019 - thelancet.com
Background Nosocomial pneumonia due to antimicrobial-resistant pathogens is associated
with high mortality. We assessed the efficacy and safety of the combination antibacterial …
with high mortality. We assessed the efficacy and safety of the combination antibacterial …
Antibiotic stewardship in the intensive care unit
CE Luyt, N Bréchot, JL Trouillet, J Chastre - Critical care, 2014 - Springer
The rapid emergence and dissemination of antimicrobial-resistant microorganisms in ICUs
worldwide constitute a problem of crisis dimensions. The root causes of this problem are …
worldwide constitute a problem of crisis dimensions. The root causes of this problem are …