The essential medicinal chemistry of curcumin: miniperspective
Curcumin is a constituent (up to∼ 5%) of the traditional medicine known as turmeric. Interest
in the therapeutic use of turmeric and the relative ease of isolation of curcuminoids has led …
in the therapeutic use of turmeric and the relative ease of isolation of curcuminoids has led …
[HTML][HTML] Free radicals, natural antioxidants, and their reaction mechanisms
The normal biochemical reactions in our body, increased exposure to the environment, and
higher levels of dietary xenobiotic's result in the generation of reactive oxygen species …
higher levels of dietary xenobiotic's result in the generation of reactive oxygen species …
[HTML][HTML] Curcumin as a photosensitizer: From molecular structure to recent advances in antimicrobial photodynamic therapy
Nowadays multi-drug resistant microorganisms is a serious public health problem
worldwide. To overcome it, new antimicrobial strategies have been developed. Among them …
worldwide. To overcome it, new antimicrobial strategies have been developed. Among them …
[HTML][HTML] Formulation of more efficacious curcumin delivery systems using colloid science: enhanced solubility, stability, and bioavailability
B Zheng, DJ McClements - Molecules, 2020 - mdpi.com
Curcumin is a bioactive constituent isolated from turmeric that has historically been used as
a seasoning, pigment, and herbal medicine in food. Recently, it has become one of the most …
a seasoning, pigment, and herbal medicine in food. Recently, it has become one of the most …
The molecular basis for the pharmacokinetics and pharmacodynamics of curcumin and its metabolites in relation to cancer
M Heger, RF van Golen, M Broekgaarden… - Pharmacological …, 2014 - ASPET
This review addresses the oncopharmacological properties of curcumin at the molecular
level. First, the interactions between curcumin and its molecular targets are addressed on …
level. First, the interactions between curcumin and its molecular targets are addressed on …
Degradation of curcumin: from mechanism to biological implications
C Schneider, ON Gordon, RL Edwards… - Journal of agricultural …, 2015 - ACS Publications
Curcumin is the main bioactive ingredient in turmeric extract and widely consumed as part of
the spice mix curry or as a dietary supplement. Turmeric has a long history of therapeutic …
the spice mix curry or as a dietary supplement. Turmeric has a long history of therapeutic …
The mechanism (s) of action of antioxidants: From scavenging reactive oxygen/nitrogen species to redox signaling and the generation of bioactive secondary …
A Hunyadi - Medicinal research reviews, 2019 - Wiley Online Library
Small molecule, dietary antioxidants exert a remarkably broad range of bioactivities, and
many of these can be explained by the influence of antioxidants on the redox homeostasis …
many of these can be explained by the influence of antioxidants on the redox homeostasis …
Mechanisms of phytonutrient modulation of cyclooxygenase-2 (COX-2) and inflammation related to cancer
SJ Desai, B Prickril, A Rasooly - Nutrition and cancer, 2018 - Taylor & Francis
The link between chronic inflammation and cancer involves cytokines and mediators of
inflammatory pathways. Cyclooxygenase-2 (COX-2), a key enzyme in fatty acid metabolism …
inflammatory pathways. Cyclooxygenase-2 (COX-2), a key enzyme in fatty acid metabolism …
Curcumin: recent advances in the development of strategies to improve oral bioavailability
KZ Sanidad, E Sukamtoh, H Xiao… - Annual review of …, 2019 - annualreviews.org
Substantial human and preclinical studies have shown that curcumin, a dietary compound
from turmeric, has a variety of health-promoting effects including but not limited to …
from turmeric, has a variety of health-promoting effects including but not limited to …
[HTML][HTML] The anti-inflammatory activity of curcumin is mediated by its oxidative metabolites
The spice turmeric, with its active polyphenol curcumin, has been used as anti-inflammatory
remedy in traditional Asian medicine for centuries. Many cellular targets of curcumin have …
remedy in traditional Asian medicine for centuries. Many cellular targets of curcumin have …