Looking at globular proteins with the eyes of a colloid scientist has a long tradition, in fact a
significant part of the early colloid literature was focused on protein solutions. However, it …

We present an overview of protein dynamics based mostly on results of neutron scattering,
dielectric relaxation spectroscopy and molecular dynamics simulations. We identify several …

The dynamics of proteins in solution includes a variety of processes, such as backbone and
side-chain fluctuations, interdomain motions, as well as global rotational and translational …

Monoclonal antibodies (mAbs) are a major class of biopharmaceuticals. It is hypothesized
that some concentrated mAb solutions exhibit formation of a solution phase consisting of …

We present detailed dielectric spectroscopy studies of dynamics in two hydrated proteins,
lysozyme and myoglobin. We emphasize the importance of explicit account for possible …

Clarification of solution structure and its modulation in proteins and protein complexes is
crucially important to understand dynamical ordering in macromolecular systems. Small …

Many enzymes undergo major conformational changes to function in cells, particularly when
they bind to more than one substrate. We quantify the large-amplitude hinge-bending …

A new method for calculating the resistance tensors of arbitrarily shaped particles and the
translational and rotational self-diffusivity in suspensions of such particles is developed. This …

Background The importance of protein dynamics for their biological activity is now well
recognized. Different experimental and computational techniques have been employed to …

Dynamic neutron scattering directly probes motions in biological systems on femtosecond to
microsecond timescales. When combined with molecular dynamics simulation and normal …