Potential therapeutic effects of antagonizing adenosine A2A receptor, curcumin and niacin in rotenone-induced Parkinson's disease mice model
Parkinson's disease (PD) is the second common age-related neurodegenerative disease. It
is characterized by control loss of voluntary movements control, resting tremor, postural …
is characterized by control loss of voluntary movements control, resting tremor, postural …
The role of KATP channel blockade and activation in the protection against neurodegeneration in the rotenone model of Parkinson's disease
NF Abdelkader, HA Farid, ER Youness… - Life Sciences, 2020 - Elsevier
Aims Several studies suggested that ATP-sensitive potassium channels (K ATP) are
potential therapeutic targets for protection against various neurodegenerative disorders, yet …
potential therapeutic targets for protection against various neurodegenerative disorders, yet …
Optimization of curcuminoids extraction for evaluation against Parkinson's disease in rats
MA Hamed, MA Mohammed… - Journal of Biologically …, 2019 - Taylor & Francis
Abstract Curcuma longa (Family, Zingiberaceae) is rich in polyphenolic compounds;
curcuminoids which is used in traditional medicine as antioxidant, anti-tumor, antimicrobial …
curcuminoids which is used in traditional medicine as antioxidant, anti-tumor, antimicrobial …
Parkinsonism-like disease induced by rotenone in rats: Treatment role of curcumin, dopamine agonist and adenosine A2A receptor antagonist
AFA Naser, WM Aziz, YR Ahmed… - Current Aging …, 2022 - ingentaconnect.com
Background: Parkinsonism is a neurodegenerative disorder that affects elderly people
worldwide. Methods: Curcumin, adenosine A2AR antagonist (ZM241385) and Sinemet®(L …
worldwide. Methods: Curcumin, adenosine A2AR antagonist (ZM241385) and Sinemet®(L …
Gene Expression, Oxidative Stress, and Neurotransmitters in Rotenone-induced Parkinson's Disease in Rats: Role of Naringin from Citrus aurantium via Blocking …
YR Ahmed, AF Aboul Naser… - Current Bioactive …, 2024 - ingentaconnect.com
Background: Lack of control in voluntary movements, resting tremor, postural instability, and
stiffness are the hallmarks of Parkinson's disease (PD). Objective: The current work's …
stiffness are the hallmarks of Parkinson's disease (PD). Objective: The current work's …
[PDF][PDF] Grape seed extract exerts an anti-apoptotic effect and attenuates the decrease in striatal tyrosine hydroxylase in rotenone-treated mice
OME Abdel-Salam, MES El-Shamarka… - Reactive Oxygen …, 2019 - academia.edu
The potential neuroprotective effect of grape seed extract (GSE) was evaluated in the
rotenoneinduced Parkinson's disease in mice. Rotenone was administered at the dose of …
rotenoneinduced Parkinson's disease in mice. Rotenone was administered at the dose of …
Natural sources, dopaminergic and non-dopaminergic agents for therapeutic assessment of Parkinsonism in rats model
MA Hamed, AFA Naser, WM Aziz, FM Ibrahim, SA Ali… - PharmaNutrition, 2020 - Elsevier
Parkinson's disease (PD) is a chronic neurodegenerative disorder affecting elderly people.
The aim of this study is to analyze the efficacy of dopaminergic and non-dopaminergic …
The aim of this study is to analyze the efficacy of dopaminergic and non-dopaminergic …
Citric acid protects dopaminergic cells against rotenone-induced neurodegeneration
OME Abdel-Salam, SMY Morsy, ER Youness… - Reactive Oxygen …, 2020 - rosj.org
We investigated the effect of citric acid on rotenone-induced oxidative stress and neuro-and
hepato-toxicity. Swiss mice received subcutaneous injections of rotenone at a dose of 1.5 …
hepato-toxicity. Swiss mice received subcutaneous injections of rotenone at a dose of 1.5 …
NEUROCHEMICAL AND HISTOLOGICAL BRAIN ALTERATIONS AFTER TRAMADOL ADMINISTRATION TO ROTENONE-INDUCED PARKINSON'S DISEASE IN …
S Elshebiney, D Abuelfadl… - The Egyptian Journal of …, 2020 - ejfsat.journals.ekb.eg
Objective: Tramadol is favorably used for relief of moderate and severe pain. Over 30% of
Parkinson's disease (PD) patients experience persistent pain that has a negative impact on …
Parkinson's disease (PD) patients experience persistent pain that has a negative impact on …