Microphysiological systems (MPS) are drawing increasing interest from academia and from
biomedical industry due to their improved capability to capture human physiology. MPS offer …

Cardiovascular diseases are a leading cause of mortality and pose a significant burden on
healthcare systems worldwide. Despite remarkable progress in medical research, the …

Neurons can regulate the development, pathogenesis, and regeneration of target organs.
However, the role of neurons during heart development and regeneration remains unclear …

Embryos devoid of autonomic innervation suffer sudden cardiac death. However, whether
autonomic neurons have a role in heart development is poorly understood. To investigate if …

Hypertrophic cardiomyopathy (HCM) is the most common inherited heart disease; its
pathogenesis is still being intensively studied to explain the reasons for the significant …

Cardiac maturation represents the last phase of heart development and is characterized by
morphofunctional alterations that optimize the heart for efficient pumping. Its understanding …

Pharmaceutical pollutants are released into the environment due to their direct outflow from
waste disposal, animal discharge, and drug manufacturing. The long-term health effects on …

This paper updates and builds on a previous White Paper in this journal that some of us
contributed to concerning the molecular and cellular basis of cardiac neurobiology of heart …

Cardiovascular disease is the leading cause of mortality worldwide. Myocardial injury
resulting from ischemia can be fatal because of the limited regenerative capacity of adult …

To identify non-cell-autonomous effectors of cardiomyocyte mitosis, we analyzed a
transcriptomic screen of regenerating and non-regenerating neonatal hearts for differentially …