Tendon explant models for physiologically relevant in vitro study of tissue biology – a perspective

SL Wunderli, U Blache, JG Snedeker - Connective tissue research, 2020 - Taylor & Francis
Background: Tendon disorders increasingly afflict our aging society but we lack the scientific
understanding to clinically address them. Clinically relevant models of tendon disease are …

Depletion of Scleraxis-lineage cells during tendon healing transiently impairs multi-scale restoration of tendon structure during early healing

A Korcari, S Muscat, E McGinn, MR Buckley… - PloS one, 2022 - journals.plos.org
Tendons are composed of a heterogeneous cell environment, with Scleraxis-lineage (Scx
Lin) cells being the predominant population. Although Scx Lin cells are required for …

Inducible depletion of Scleraxis-lineage cells during tendon healing impairs multi-scale restoration of tendon structure

A Korcari, S Muscat, MR Buckley, AE Loiselle - bioRxiv, 2022 - biorxiv.org
Tendons are composed of a heterogeneous cell environment, with Scleraxis-lineage (Scx
Lin) cells being the predominant population. Although Scx Lin cells are required for …

[图书][B] Deciphering the Functions of Scleraxis-Lineage (ScxLin) Cells to Define Cellular and Molecular Programs Responsible for Tendon Homeostasis Maintenance …

A Korcari - 2022 - search.proquest.com
During adulthood, tendon homeostasis is maintained via ongoing turnover of extracellular
matrix (ECM) components. However, during aging, declines in tendon structure-function are …

[图书][B] G protein-coupled receptor-mediated transcriptional regulation in pathological cardiac remodelling

RD Martin - 2020 - search.proquest.com
Pathological cardiac remodelling is an adaptive response to various stressors placed on the
heart, such as sustained hypertension or following myocardial infarction. The remodelling …