Infection with Helicobacter pylori is a primary culprit in the etiology of gastric disease, and its
cell-wall lipopolysaccharide (LPS) is recognized as a potent endotoxin responsible for …

Generally, most of ovarian cancer cannot be detected until large scale and remote
metastasis occurs, which is the major cause of high mortality in ovarian cancer. Therefore, it …

Pancreatic cancer is the worst exocrine gastrointestinal cancer leading to the highest
mortality. Recent studies reported that aberrant expression of apurinic/apyrimidinic …

Chondrosarcoma is the second most common primary malignancy form of bone cancer,
exhibiting resistance to chemotherapy and radiation therapy as well as developing high …

Bladder cancer is a leading human malignancy worldwide. Signal transducer and activator
of transcription (STAT) 3 is an oncogenic transcription factor commonly hyperactivated in …

Small-cell lung cancer (SCLC) is a highly metastatic and recalcitrant malignancy. Metastasis
is the major cause of death in patients with SCLC but its mechanism remains poorly …

Among the key factors defining the extent of gastric mucosal inflammatory involvement in
response to Helicobacter pylori is the excessive generation of prostaglandin (PGE 2) and …

Abstract Natural and synthetic (−)-kusunokinin inhibited breast cancer, colon cancer and
cholangiocarcinoma cells at the G2/M phase and induced apoptosis. However, there is no …

The receptor tyrosine kinase (RTK) Ror2 plays important roles in developmental
morphogenesis and mediates the filopodia formation in Wnt5a-induced cell migration …

Human neural stem cells (hNSCs) can differentiate into an oligodendrocyte lineage to
facilitate remyelination in patients. Molecular mechanisms underlying oligodendrocyte fate …