The role of immune cells and mediators in preeclampsia

E Deer, O Herrock, N Campbell, D Cornelius… - Nature Reviews …, 2023 - nature.com
Preeclampsia is a hypertensive disorder of major concern in pregnancy than can lead to
intrauterine growth restriction, placental abruption and stillbirth. The pathophysiology of …

Mechanisms of key innate immune cells in early-and late-onset preeclampsia

I Aneman, D Pienaar, S Suvakov, TP Simic… - Frontiers in …, 2020 - frontiersin.org
Preeclampsia is a complex cardiovascular disorder of pregnancy with underlying
multifactorial pathogeneses; however, its etiology is not fully understood. It is characterized …

Placental lesions associated with maternal underperfusion are more frequent in early-onset than in late-onset preeclampsia

G Ogge, T Chaiworapongsa, R Romero… - Journal of perinatal …, 2011 - degruyter.com
Objective: Preeclampsia (PE) has been classified into early-and late-onset disease. These
two phenotypic variants of PE have been proposed to have a different pathophysiology …

Placental pathology suggesting that preeclampsia is more than one disease

DB Nelson, MS Ziadie, DD McIntire, BB Rogers… - American journal of …, 2014 - Elsevier
Objective Our purpose was to evaluate the placental pathology in women with preeclampsia
occurring at varying gestational ages. Study Design This was a secondary analysis of a …

Ранняя и поздняя преэклампсия: парадигмы патобиологии и клиническая практика

ЗС ХОДЖАЕВА, АМ ХОЛИН… - Акушерство и …, 2013 - elibrary.ru
Преэклампсия (ПЭ) остается ведущей причиной материнской и перинатальной
смертности и заболеваемости. За последние десятилетия расширились …

Neutrophil NETs in reproduction: from infertility to preeclampsia and the possibility of fetal loss

S Hahn, S Giaglis, I Hoesli, P Hasler - Frontiers in immunology, 2012 - frontiersin.org
The intention of this review is to provide an overview of the potential role of neutrophil
extracellular traps (NETs) in mammalian reproduction. Neutrophil NETs appear to be …

Inflammatory disturbances in preeclampsia: relationship between maternal and umbilical cord blood

C Catarino, A Santos-Silva, L Belo… - Journal of …, 2012 - Wiley Online Library
Preeclampsia (PE) is one of the main causes of maternal and fetal mortality and morbidity.
PE is associated with an inflammatory state and with oxidative stress, in maternal circulation …

New immune horizons in therapeutics and diagnostic approaches to Preeclampsia

I Mukherjee, S Singh, A Karmakar… - American Journal of …, 2023 - Wiley Online Library
Hypertensive disorders of pregnancy (HDP) are one of the commonest maladies, affecting
5%–10% of pregnancies worldwide. The American College of Obstetricians and …

Resolution of inflammation pathways in preeclampsia—a narrative review

LO Perucci, MD Corrêa, LM Dusse, KB Gomes… - Immunologic …, 2017 - Springer
Preeclampsia (PE) is one of the leading causes of maternal morbidity and mortality
worldwide. This disease is believed to occur in two stages with placental dysfunction in early …

Leukocyte activation and circulating leukocyte‐derived microparticles in preeclampsia

CAR Lok, J Jebbink, R Nieuwland… - American journal of …, 2009 - Wiley Online Library
Problem Preeclampsia shows characteristics of an inflammatory disease including leukocyte
activation. Analyses of leukocyte‐derived microparticles (MP) and mRNA expression of …