Locomotion through the environment is important because movement provides access to
key resources, including food, shelter and mates. Central to many locomotion-focused …

Background Musculoskeletal modelling is a common means by which to non-invasively
analyse movement. Such models have largely been used to observe function in both healthy …

Joint tissue mechanics (eg, stress and strain) are believed to have a major involvement in
the onset and progression of musculoskeletal disorders, eg, knee osteoarthritis (KOA) …

In this chapter, we introduce musculoskeletal modelling and how such models can be
applied to estimate internal quantities that are difficult or impossible to measure …

Tissue-level mechanics (eg, stress and strain) are important factors governing tissue
remodeling and development of knee osteoarthritis (KOA), and hence, the success of …

Reconstructing the locomotor behavior of extinct animals depends on elucidating the
principles that link behavior, function, and morphology, which can only be done using extant …

Gait modification is a common nonsurgical approach to alter the mediolateral distribution of
knee contact forces, intending to decelerate or postpone the progression of mechanically …

The first peak of the external knee abduction moment (KAM) is often used as a surrogate
measure of the medial compartment loading and has been correlated with pain and …

There remains no established treatment for knee osteoarthritis (KOA), underscoring the
necessity for personalized musculoskeletal models to tailor treatment approaches. In this …

This dissertation evaluates the effect of gait modifications on the joint reaction forces (JRF)
estimated via computer simulation using the OpenSim software tool. Osteoarthritis (OA) of …