UV-based phototherapy (including psoralen plus UVA (PUVA), UVB and UVA1) has a long,
successful history in the management of numerous cutaneous disorders. Photoresponsive …

Cutaneous T cell lymphomas (CTCLs) are a heterogeneous group of extranodal non-
Hodgkin's lymphomas that are characterized by a cutaneous infiltration of malignant …

Abstract Interleukin (IL)-9 belongs to the IL-2Rγc chain family and is a multifunctional
cytokine that can regulate the function of many kinds of cells. It was originally identified as a …

ABSTRACT Cutaneous T-Cell Lymphomas (CTCL) are rare, but potentially devastating
malignancies, whose pathogenesis remains poorly elucidated. Unfortunately, currently it is …

Backgrounds Cutaneous T cell lymphoma (CTCL) is a non-Hodgkin lymphoma
characterized by skin infiltration of malignant T cells. The biological overlap between …

Deficient expression of SATB1 hampers thymocyte development and results in inept T-cell
lineages. Recent data implicate dysregulated SATB1 expression in the pathogenesis of …

Abstract Mycosis Fungoides (MF) and Sézary Syndrome (SS) belong to a wide spectrum of T
cell lymphoproliferative disorders collectively termed cutaneous T cell lymphomas (CTCL) …

Interleukin 9 secreting TH 9 cells have been proposed as the latest addition to the family of T
helper cell subsets. While a growing body of evidence from animal models points to …

In cutaneous T cell lymphomas (CTCL), miR-21 is aberrantly expressed in skin and
peripheral blood and displays anti-apoptotic properties in malignant T cells. It is, however …

Importance Psoralen–UV-A (PUVA) photochemotherapy is standard first-line treatment for
skin-limited, early-stage mycosis fungoides capable of producing high initial complete …