The physiological functions of human peroxisomes
RJA Wanders, M Baes, D Ribeiro… - Physiological …, 2023 - journals.physiology.org
Peroxisomes are subcellular organelles that play a central role in human physiology by
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …
Peroxisome biogenesis
PE Purdue, PB Lazarow - Annual review of cell and …, 2001 - annualreviews.org
▪ Abstract Fifteen years ago, we had a model of peroxisome biogenesis that involved growth
and division of preexisting peroxisomes. Today, thanks to genetically tractable model …
and division of preexisting peroxisomes. Today, thanks to genetically tractable model …
COVID‐19 induces neuroinflammation and suppresses peroxisomes in the brain
A Roczkowsky, D Limonta, JP Fernandes… - Annals of …, 2023 - Wiley Online Library
Objective Peroxisome injury occurs in the central nervous system (CNS) during multiple
virus infections that result in neurological disabilities. We investigated host neuroimmune …
virus infections that result in neurological disabilities. We investigated host neuroimmune …
Peroxisomal targeting signal receptor Pex5p interacts with cargoes and import machinery components in a spatiotemporally differentiated manner: conserved Pex5p …
H Otera, K Setoguchi, M Hamasaki… - … and cellular biology, 2002 - Taylor & Francis
Two isoforms of the peroxisomal targeting signal type 1 (PTS1) receptor, termed Pex5pS
and (37-amino-acid-longer) Pex5pL, are expressed in mammals. Pex5pL transports PTS1 …
and (37-amino-acid-longer) Pex5pL, are expressed in mammals. Pex5pL transports PTS1 …
Peroxisome biogenesis in mammalian cells
Y Fujiki, K Okumoto, S Mukai, M Honsho… - Frontiers in …, 2014 - frontiersin.org
To investigate peroxisome assembly and human peroxisome biogenesis disorders (PBDs)
such as Zellweger syndrome, thirteen different complementation groups (CGs) of Chinese …
such as Zellweger syndrome, thirteen different complementation groups (CGs) of Chinese …
Peroxisome biogenesis, membrane contact sites, and quality control
Peroxisomes are conserved organelles of eukaryotic cells with important roles in cellular
metabolism, human health, redox homeostasis, as well as intracellular metabolite transfer …
metabolism, human health, redox homeostasis, as well as intracellular metabolite transfer …
Peroxisomal membrane proteins contain common Pex19p-binding sites that are an integral part of their targeting signals
H Rottensteiner, A Kramer, S Lorenzen… - Molecular biology of …, 2004 - Am Soc Cell Biol
Targeting of peroxisomal membrane proteins (PMPs) is a multistep process that requires not
only recognition of PMPs in the cytosol but also their insertion into the peroxisomal …
only recognition of PMPs in the cytosol but also their insertion into the peroxisomal …
[HTML][HTML] Protein import machineries of peroxisomes
R Rucktäschel, W Girzalsky, R Erdmann - Biochimica et Biophysica Acta …, 2011 - Elsevier
Peroxisomes are a class of structurally and functionally related organelles present in almost
all eukaryotic cells. The importance of peroxisomes for human life is highlighted by severe …
all eukaryotic cells. The importance of peroxisomes for human life is highlighted by severe …
The peroxisomal membrane protein import receptor Pex3p is directly transported to peroxisomes by a novel Pex19p-and Pex16p-dependent pathway
T Matsuzaki, Y Fujiki - The Journal of cell biology, 2008 - rupress.org
Two distinct pathways have recently been proposed for the import of peroxisomal membrane
proteins (PMPs): a Pex19p-and Pex3p-dependent class I pathway and a Pex19p-and Pex3p …
proteins (PMPs): a Pex19p-and Pex3p-dependent class I pathway and a Pex19p-and Pex3p …
The membrane peroxin PEX3 induces peroxisome-ubiquitination-linked pexophagy
S Yamashita, K Abe, Y Tatemichi, Y Fujiki - Autophagy, 2014 - Taylor & Francis
Peroxisomes are degraded by a selective type of autophagy known as pexophagy. Several
different types of pexophagy have been reported in mammalian cells. However, the …
different types of pexophagy have been reported in mammalian cells. However, the …