Stachybotrys chartarum—A Hidden Treasure: Secondary Metabolites, Bioactivities, and Biotechnological Relevance
Fungi are renowned as a fountainhead of bio-metabolites that could be employed for
producing novel therapeutic agents, as well as enzymes with wide biotechnological and …
producing novel therapeutic agents, as well as enzymes with wide biotechnological and …
Chaetomugilins and chaetoviridins—promising natural metabolites: structures, separation, characterization, biosynthesis, bioactivities, molecular docking, and …
Fungi are recognized as luxuriant metabolic artists that generate propitious biometabolites.
Historically, fungal metabolites have largely been investigated as leads for various …
Historically, fungal metabolites have largely been investigated as leads for various …
Depside bond formation by the starter-unit acyltransferase domain of a fungal polyketide synthase
Depsides are polyphenolic molecules comprising two or more phenolic acid derivatives
linked by an ester bond, which is called a depside bond in these molecules. Despite more …
linked by an ester bond, which is called a depside bond in these molecules. Despite more …
Didepside Formation by the Nonreducing Polyketide Synthase Preu6 of Preussia isomera Requires Interaction of Starter Acyl Transferase and Thioesterase Domains
Q Liu, D Zhang, S Gao, X Cai, M Yao… - Angewandte Chemie …, 2023 - Wiley Online Library
Orsellinic acid (OA) derivatives are produced by filamentous fungi using nonreducing
polyketide synthases (nrPKSs). The chain‐releasing thioesterase (TE) domains of such …
polyketide synthases (nrPKSs). The chain‐releasing thioesterase (TE) domains of such …
Terretonin as a new protective agent against sepsis-induced acute lung injury: Impact on SIRT1/Nrf2/NF-κBp65/NLRP3 signaling
Simple Summary Acute lung injury (ALI) is a severe inflammatory pulmonary disorder that
still causes a high mortality rate. As the current therapeutic strategies have not been effective …
still causes a high mortality rate. As the current therapeutic strategies have not been effective …
Fungal naphthalenones; promising metabolites for drug discovery: Structures, biosynthesis, sources, and pharmacological potential
SRM Ibrahim, SA Fadil, HA Fadil, BA Eshmawi… - Toxins, 2022 - mdpi.com
Fungi are well-known for their abundant supply of metabolites with unrivaled structure and
promising bioactivities. Naphthalenones are among these fungal metabolites, that are …
promising bioactivities. Naphthalenones are among these fungal metabolites, that are …
Aspergillus ochraceus: Metabolites, Bioactivities, Biosynthesis, and Biotechnological Potential
RH Hareeri, MM Aldurdunji, HM Abdallah, AA Alqarni… - Molecules, 2022 - mdpi.com
Fungus continues to attract great attention as a promising pool of biometabolites. Aspergillus
ochraceus Wilh (Aspergillaceae) has established its capacity to biosynthesize a myriad of …
ochraceus Wilh (Aspergillaceae) has established its capacity to biosynthesize a myriad of …
Extracellular Vesicles from Candida haemulonii var. vulnera Modulate Macrophage Oxidative Burst
BTM Oliveira, TMH Dourado, PWS Santos… - Journal of Fungi, 2023 - mdpi.com
Members of the Candida haemulonii species complex are multidrug-resistant emergent
yeast pathogens able to cause superficial and invasive infections in risk populations. Fungal …
yeast pathogens able to cause superficial and invasive infections in risk populations. Fungal …
Docking and molecular dynamic investigations of phenylspirodrimanes as cannabinoid receptor-2 agonists
Cannabinoid receptor ligands are renowned as being therapeutically crucial for treating
diverse health disorders. Phenylspirodrimanes are meroterpenoids with unique and varied …
diverse health disorders. Phenylspirodrimanes are meroterpenoids with unique and varied …
Aspergillus nidulans—Natural Metabolites Powerhouse: Structures, Biosynthesis, Bioactivities, and Biotechnological Potential
KF Ghazawi, SA Fatani, SGA Mohamed, GA Mohamed… - Fermentation, 2023 - mdpi.com
Nowadays, finding out new natural scaffolds of microbial origin increases at a higher rate
than in the past decades and represents an auspicious route for reinvigorating the pool of …
than in the past decades and represents an auspicious route for reinvigorating the pool of …