[HTML][HTML] Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer's disease
Alzheimer's disease (AD) is the most common neurodegenerative disorder seen in age-
dependent dementia. There is currently no effective treatment for AD, which may be …
dependent dementia. There is currently no effective treatment for AD, which may be …
[HTML][HTML] History and progress of hypotheses and clinical trials for Alzheimer's disease
PP Liu, Y Xie, XY Meng, JS Kang - Signal transduction and targeted …, 2019 - nature.com
Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive
memory loss along with neuropsychiatric symptoms and a decline in activities of daily life. Its …
memory loss along with neuropsychiatric symptoms and a decline in activities of daily life. Its …
[HTML][HTML] Mechanisms and treatment of late-life depression
GS Alexopoulos - Translational psychiatry, 2019 - nature.com
Depression predisposes to medical illnesses and advances biological aging indicated by
shorter telomere length, accelerated brain aging and advanced epigenetic aging. Medical …
shorter telomere length, accelerated brain aging and advanced epigenetic aging. Medical …
[HTML][HTML] Depression—an underrecognized target for prevention of dementia in Alzheimer's disease
FS Dafsari, F Jessen - Translational psychiatry, 2020 - nature.com
It is broadly acknowledged that the onset of dementia in Alzheimer's disease (AD) may be
modifiable by the management of risk factors. While several recent guidelines and …
modifiable by the management of risk factors. While several recent guidelines and …
Extracellular vesicles round off communication in the nervous system
Functional neural competence and integrity require interactive exchanges among sensory
and motor neurons, interneurons and glial cells. Recent studies have attributed some of the …
and motor neurons, interneurons and glial cells. Recent studies have attributed some of the …
[HTML][HTML] Alzheimer's disease and gut microbiota
X Hu, T Wang, F Jin - Science China Life Sciences, 2016 - Springer
Alzheimer's disease (AD) is a most common neurodegenerative disorder, which associates
with impaired cognition. Gut microbiota can modulate host brain function and behavior via …
with impaired cognition. Gut microbiota can modulate host brain function and behavior via …
[HTML][HTML] Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases
The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …
[HTML][HTML] Microbiota-gut-brain axis and the central nervous system
X Zhu, Y Han, J Du, R Liu, K Jin, W Yi - Oncotarget, 2017 - ncbi.nlm.nih.gov
The gut and brain form the gut-brain axis through bidirectional nervous, endocrine, and
immune communications. Changes in one of the organs will affect the other organs …
immune communications. Changes in one of the organs will affect the other organs …
[HTML][HTML] The role of serotonin within the microbiota-gut-brain axis in the development of Alzheimer's disease: A narrative review
E Aaldijk, Y Vermeiren - Ageing Research Reviews, 2022 - Elsevier
Alzheimer's disease (AD) is the most common cause of dementia, accounting for more than
50 million patients worldwide. Current evidence suggests the exact mechanism behind this …
50 million patients worldwide. Current evidence suggests the exact mechanism behind this …
[HTML][HTML] Increased microglial exosomal miR-124-3p alleviates neurodegeneration and improves cognitive outcome after rmTBI
X Ge, M Guo, T Hu, W Li, S Huang, Z Yin, Y Li, F Chen… - Molecular Therapy, 2020 - cell.com
Repetitive mild traumatic brain injury (rmTBI) is considered to be an important risk factor for
long-term neurodegenerative disorders such as Alzheimer's disease, which is characterized …
long-term neurodegenerative disorders such as Alzheimer's disease, which is characterized …